Relationship Between Preoperative Alcohol Consumption and Postoperative Nausea and Vomiting in Liver Resection: A Propensity Score Matched Analysis in a Single Institute.

Q3 Medicine
Y. Yamamoto, Yusuke Naito, H. Nakatani, M. Ida, M. Kawaguchi
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引用次数: 0

Abstract

BACKGROUND Patients with alcohol drinking habits have less nausea and vomiting during chemotherapy because of cytochrome P450 enzyme induction. However, few studies have examined the effect of alcohol consumption on postoperative nausea and vomiting (PONV). We conducted a study to clarify the relationship between alcohol drinking habits and PONV. METHODS Data of patients undergoing hepatectomy under general anesthesia between 2016 and 2020 were retrospectively collected. Since alcohol drinking habits vary by gender, age, and comorbidities, propensity score matching was performed to adjust patient background before multivariate logistic regression analysis. RESULTS Seventy-eight patients in the alcohol consumption and non-consumption groups were matched by propensity matching. Univariate analysis showed that alcohol consumption (P = 0.04) and male (P < 0.001) were the factors that significantly reduced PONV. Multiple logistic regression analysis including intraoperative factors showed that alcohol consumption (odds ratio, 0.36; 95% confidence interval [CI], 0.15-0.90) and female (odds ratio, 5.34; 95% CI, 2.0-14.2) were associated with PONV as factors affecting PONV. CONCLUSION Patients with no alcohol drinking habits may be at higher risk of PONV.
肝切除术前饮酒与术后恶心呕吐的关系:单一研究所的倾向评分匹配分析。
背景有饮酒习惯的患者在化疗期间,由于细胞色素P450酶的诱导,恶心和呕吐较少。然而,很少有研究检测饮酒对术后恶心呕吐(PONV)的影响。我们进行了一项研究,以阐明饮酒习惯与PONV之间的关系。方法回顾性收集2016年至2020年间在全麻下接受肝切除术的患者的数据。由于饮酒习惯因性别、年龄和合并症而异,在进行多元逻辑回归分析之前,进行倾向评分匹配以调整患者背景。结果对饮酒组和非饮酒组的8例患者进行倾向匹配。单因素分析显示,饮酒(P=0.04)和男性(P<0.001)是显著降低PONV的因素。包括术中因素在内的多元logistic回归分析显示,饮酒(比值比0.36;95%可信区间[CI],0.15-0.90)和女性(比值比5.34;95%置信区间2.0-14.2)与PONV相关,是影响PONV的因素。
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来源期刊
Asian journal of anesthesiology
Asian journal of anesthesiology Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
38
期刊介绍: Asian Journal of Anesthesiology (AJA), launched in 1962, is the official and peer-reviewed publication of the Taiwan Society of Anaesthesiologists. It is published quarterly (March/June/September/December) by Airiti and indexed in EMBASE, Medline, Scopus, ScienceDirect, SIIC Data Bases. AJA accepts submissions from around the world. AJA is the premier open access journal in the field of anaesthesia and its related disciplines of critical care and pain in Asia. The number of Chinese anaesthesiologists has reached more than 60,000 and is still growing. The journal aims to disseminate anaesthesiology research and services for the Chinese community and is now the main anaesthesiology journal for Chinese societies located in Taiwan, Mainland China, Hong Kong and Singapore. AJAcaters to clinicians of all relevant specialties and biomedical scientists working in the areas of anesthesia, critical care medicine and pain management, as well as other related fields (pharmacology, pathology molecular biology, etc). AJA''s editorial team is composed of local and regional experts in the field as well as many leading international experts. Article types accepted include review articles, research papers, short communication, correspondence and images.
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