Single or Dual Infection with Respiratory Syncytial Virus and Human Rhinovirus: Epidemiology and Clinical Characteristics in Hospitalized Children in a Rural Area of South Korea

Q3 Medicine

Pediatric Infection and Vaccine Pub Date : 2019-08-01 DOI:10.14776/PIV.2019.26.E11

Y. Kwon, Won Je Cho, Hwang-Min Kim, Jeongmin Lee

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引用次数: 2

Abstract

Purpose: Respiratory syncytial virus (RSV) and human rhinovirus (hRV) are the most common causes of child respiratory viral infections. We aimed to investigate epidemiological and clinical characteristics of RSV and hRV single infections and coinfections. Methods: Nasopharyngeal aspirates of hospitalized children aged <5 years were tested using multiplex reverse transcription polymerase chain reaction (RT-PCR) from October 2014 to April 2017. Their medical records were retrospectively reviewed. Results: RSV or hRV was detected in 384 patients who divided into 3 groups: patients with RSV (R group, n=258); patients with hRV (H group, n=99); and patients with both (RH group, n=27). The R group (median age, 6 months) consisted of 248 (96.1%) patients with lower respiratory tract infection (LRTI), and 14 (5.4%) needed oxygen inhalation. Infants aged <12 months (63.2%) had respiratory difficulty and were supplied oxygen more often. The H group (median age, 16 months) consisted of 56 (56.6%) patients with LRTI, 4 (4%) required oxygen inhalation, and 1 (1.0%) required mechanical ventilation. Infants (40.4%) showed longer hospitalization compared to patients aged ≥12 months (5 vs. 4 days, P<0.05). The RH group consisted of 24 (88.9%) patients with LRTI, and 2 (7.4%) needed oxygen inhalation. Hospitalization days and oxygen inhalation and mechanical ventilation rates did not differ Pediatr Infect Vaccine. 2019 Aug;26(2):99-111 https://doi.org/10.14776/piv.2019.26.e11 pISSN 2384-1079·eISSN 2384-1087

查看原文本刊更多论文

呼吸道合胞病毒和人鼻病毒的单一或双重感染:韩国农村住院儿童的流行病学和临床特征

目的：呼吸道合胞病毒（RSV）和人鼻病毒（hRV）是儿童呼吸道病毒感染的最常见原因。我们旨在调查呼吸道合胞病毒和hRV单一感染和合并感染的流行病学和临床特征。方法：2014年10月至2017年4月，采用多重逆转录聚合酶链式反应（RT-PCR）对5岁以下住院儿童的鼻咽分泌物进行检测。对他们的医疗记录进行了回顾性审查。结果：在384例患者中检测到RSV或hRV，分为3组：RSV患者（R组，n=258）；hRV患者（H组，n=99）；两组患者（RH组，n=27）。R组（中位年龄，6个月）包括248名（96.1%）下呼吸道感染（LRTI）患者，14名（5.4%）需要吸氧。<12个月大的婴儿（63.2%）有呼吸困难，并且氧气供应更频繁。H组（中位年龄，16个月）包括56名（56.6%）LRTI患者，4名（4%）需要吸氧，1名（1.0%）需要机械通气。与年龄≥12个月的患者相比，婴儿（40.4%）的住院时间更长（5天与4天，P<0.05）。RH组由24名（88.9%）LRTI患者组成，2名（7.4%）需要吸氧。住院天数、吸氧率和机械通气率没有差异。2019年8月；26（2）：99-111https://doi.org/10.14776/piv.2019.26.e11pISSN 2384-1079·eISSN 2384-1087

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来源期刊

Pediatric Infection and Vaccine Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Pediatric Infection and Vaccine is an official publication of the Korean Society of Pediatric Infectious Diseases and a peer-reviewed, open-access, multidisciplinary journal directed to physicians and other health care professionals who manage infectious diseases of childhood. The editorial board calls for the articles that originate from worldwide research or clinical study groups and the publication is determined by the editors and reviewers who are the experts in the specific field of infectious diseases of childhood. The categories of manuscripts are original articles, case reports, reviews and rapid communication. The Journal is published triannually and distributed to members of the Korean Society of Pediatric Infectious Diseases, medical schools, libraries and related institutes to persue the academic advancement in infectious diseases and to promote active communication between the members and international societies of pediatric infectious diseases. Eventually, the journal aims to contribute to the cure of infectious diseases of childhood and to the improvement of public health.