To study the diagnostic accuracy of diabetes in pregnancy study group of india (DIPSI) as compared with international association of diabetes in pregnancy study group (IADPSG) Criteria in pregnancy

Abstract

Background: Hyperglycemia in pregnancy is associated with adverse maternal and perinatal outcomes. Hence, it is essential to diagnose early and treat to prevent adverse complications. The study aims to ascertain the diagnostic accuracy of the Diabetes in Pregnancy Study Group of India (DIPSI) versus the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria. Methods: Women (n = 200) attending the outpatient or inpatient department of obstetrics and gynecology with gestational age 24–28 weeks were included. As per the DIPSI and IADPSG criteria, all women underwent nonfasting oral glucose tolerance test irrespective of the last meal and after an overnight fast of at least 8 h. A venous blood sample was drawn after glucose administration and was measured by hexokinase technique using an autoanalyzer. Results: Out of 200 women, 47 (23.5%) were diagnosed with gestational diabetes mellitus (GDM) by the IADPSG, whereas 15 (7.5%) were diagnosed with GDM by DIPSI test. Sociodemographic and obstetric characteristics were comparable between the two groups. Women with a history of polycystic ovarian syndrome (odds ratio [OR]: 13.51), family history of DM (OR: 7.02), GDM (OR: 5.8), and perinatal mortality (OR: 4.27) had higher odds of developing GDM. The sensitivity and specificity of DIPSI were 27.66% and 98.69%, respectively, and diagnostic accuracy was 82%. IADPSG test can be recommended as a primary modality of screening GDM in all pregnant women. DIPSI test can be recommended for screening of the patient in non-fasting condition. Hence, by routine IADPSG test and selective DIPSI test, the whole of the antenatal population can be screened without jeopardizing the sensitivity for detection of true cases.