The effectiveness of metacognitive therapy in comparison to exposure and response prevention for obsessive-compulsive disorder: A randomized controlled trial

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-01-01 DOI:10.1016/j.jocrd.2023.100780

Kim Melchior , Colin van der Heiden , Mathijs Deen , Birgit Mayer , Ingmar H.A. Franken

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引用次数: 1

Abstract

Background

The recommended psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure with response prevention (ERP). Although this treatment is quite effective, recovery rates are modest and attrition rate is relatively high. Also, ERP treatment requires amounts of therapist time. A possible way to improve OCD treatment is by taking into account key cognitive processes involved in the development and maintenance of the disorder. The metacognitive model is such an account and pilot findings suggest that the associated metacognitive therapy (MCT) might be an effective treatment for OCD.

Methods

In the present study, a randomized controlled trial (RCT) is used to assess the effectiveness of MCT in comparison to ERP in an outpatient clinical sample of patients with OCD.

Results

Both MCT and ERP produced significant pre-treatment to post-treatment decreases in obsessive-compulsive, comorbid psychological symptoms and metacognitive beliefs, both with moderate to large within-group effect sizes and high proportions of significant clinical change. Drop-out rates were low and treatment gains were maintained at six-month follow-up. There were no differences in efficacy observed between MCT and ERP treatments.

Conclusions

MCT proves to be a promising treatment of OCD.

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元认知疗法与暴露和反应预防治疗强迫症的有效性比较:一项随机对照试验

背景强迫症(OCD)的推荐心理治疗选择是暴露与反应预防(ERP)。虽然这种治疗相当有效，但恢复率一般，损耗率相对较高。此外，ERP治疗需要大量的治疗师时间。改善强迫症治疗的一种可能方法是考虑到与强迫症发展和维持有关的关键认知过程。元认知模型就是这样一种解释，试点结果表明，相关的元认知疗法(MCT)可能是治疗强迫症的有效方法。方法本研究采用随机对照试验(RCT)评估MCT与ERP在强迫症患者门诊临床样本中的有效性。结果MCT和ERP治疗前后在强迫症、共病心理症状和元认知信念方面均显著降低，组内效应量均为中等至较大，显著临床改变比例较高。退出率很低，治疗效果在六个月的随访中保持不变。在MCT和ERP治疗之间没有观察到疗效差异。结论smct是治疗强迫症的有效方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.