Steroid Pulse Therapy in the Management of Neuro-psychiatric Manifestations in an Atypical Presentation of Typhoid Fever

Abstract

The Typhoid fever often presents with a variety of clinical symptoms and numerous systemic complications. Neurological complications of enteric fever are relatively insidious and rare and many times late and often undiagnosed complication of typhoid fever which can change the course of illness. This is a case of blood culture-proven typhoid fever with neuropsychiatric manifestations responded well with appropriate antibiotics and steroid pulse therapy (1 gram Methylprednisolone for 3 days).