Small-Fiber Neuropathy Possibly Associated with COVID-19

IF 0.6 Q4 CLINICAL NEUROLOGY

Case Reports in Neurology Pub Date : 2022-04-22 DOI:10.1159/000524205

A. Burakgazi

引用次数: 7

Abstract

COVID-19 has caused several neurological complications by affecting the central and peripheral nervous systems (PNS). Studies on the PNS involvement in COVID-19 are limited. These complications are likely unreported, given the difficulty of obtaining further diagnostic information, such as expert neurologist evaluation, electrodiagnostic testing, and skin biopsy. Herein, we report 2 cases of possible COVID-19-related small-fiber neuropathy (SFN). These cases are reported to increase awareness of a possible link between COVID-19 and SFN. Additional investigation, including neurology consultation, nerve conduction studies, and skin biopsy, should be considered in patients who develop paresthesia during and after COVID-19 infection. Further research is also needed to determine a possible underlying neuropathology mechanism and the role of immunomodulatory treatment, such as intravenous immunoglobulin, in COVID-19-related SFN.

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可能与新冠肺炎相关的小纤维神经病变

新冠肺炎通过影响中枢和外周神经系统（PNS），导致了几种神经并发症。关于PNS参与新冠肺炎的研究有限。考虑到难以获得进一步的诊断信息，如神经科专家评估、电诊断测试和皮肤活检，这些并发症可能未报告。在此，我们报告了2例可能与COVID-19相关的小纤维神经病（SFN）。据报道，这些病例是为了提高人们对新冠肺炎与SFN之间可能联系的认识。对于在新冠肺炎感染期间和之后出现感觉异常的患者，应考虑进行额外的调查，包括神经科咨询、神经传导研究和皮肤活检。还需要进一步的研究来确定潜在的神经病理学机制以及免疫调节治疗（如静脉注射免疫球蛋白）在COVID-19相关SFN中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Case Reports in Neurology Medicine-Neurology (clinical)

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： This new peer-reviewed online-only journal publishes original case reports covering the entire spectrum of neurology. Clinicians and researchers are given a tool to disseminate their personal experience to a wider public as well as to review interesting cases encountered by colleagues all over the world. To complement the contributions supplementary material is welcomed. The reports are searchable according to the key words supplied by the authors; it will thus be possible to search across the entire growing collection of case reports with universally used terms, further facilitating the retrieval of specific information. Following the open access principle, the entire contents can be retrieved at no charge, guaranteeing easy access to this valuable source of anecdotal information at all times.