Frequency and types of chromosomal abnormalities in acute lymphoblastic leukemia patients in Turkey

Abstract

Objectives: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children and is usually associated with numerical and structural chromosomal changes. The correlations of specifi c cytogenetic fi ndings with presenting clinical features indicate the prognostic signifi cance of chromosomal abnormalities (CAs) in patients with ALL.