Development of Ethosomal Gel from Withania Somnifera

Abstract

Novel drug delivery systems are used to increase administration of drugs through transdermal system. Ethosomes has the ability to permeate through the stratum corneum. Ethosomes are the delivery carriers that enable the drugs to reach the deep skin layers as well as the systemic circulation. These vesicles are well known for their importance in cellular communication and in particle transportation for many years. This article reviews various aspects of ethosomes which includes their preparation, characterization, advantages and their applications in drug delivery. Ethosomes has number of important benefits such as, it improves the drug’s efficacy, enhances the patient compliance, comfort and reduces the total cost of treatment.