Anticoagulant-induced pseudothrombocytopenia after a plasmodium falciparum infection in a five-year-old child.

Q4 Medicine
M. Igala, L. Kouegnigan Rerambiah, L. E. Ledaga Lentombo, A. Ifoudji Makao, S. N. Nto'o Eyene, S. W. Mbiye Cheme, M. B. Bouyou Akotet, J. Boguikouma
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引用次数: 3

Abstract

Pseudothrombocytopenia or artefactual thrombocytopenia is an abnormally low number of platelets due to their agglutination in a sample tube, with no ex vivo clinical translation. It occurs in ethylene diamine tetraacetic (EDTA) test tubes. Non-EDTA anticoagulants, such as citrate, fluoride oxalate, and heparin lithium, may be responsible for it, alone or in combination. It can occur in patients with autoimmune diseases, neoplasia, atherosclerosis, liver disease, or infections. We report the case of a 5-year-old child, who after falciparum malaria showed persistent thrombocytopenia. Further exploration has led to the conclusion of pseudothrombocytopenia due to three anticoagulants: EDTA, citrate, and fluoride oxalate.
一名五岁儿童恶性疟原虫感染后抗凝剂诱导的假性血小板减少症。
假性血小板减少症或人工血小板减少症是由于它们在样管中凝集而导致血小板数量异常低,没有体外临床转化。它发生在乙二胺四乙酸(EDTA)试管中。非edta抗凝剂,如柠檬酸盐、草酸氟和肝素锂,单独或联合使用都可能是原因。它可以发生在自身免疫性疾病、肿瘤、动脉粥样硬化、肝脏疾病或感染的患者身上。我们报告的情况下,一个5岁的孩子,谁后恶性疟疾表现出持续的血小板减少。进一步的研究得出结论,假性血小板减少症是由于三种抗凝剂:EDTA、柠檬酸盐和草酸氟。
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来源期刊
Medecine et sante tropicales
Medecine et sante tropicales TROPICAL MEDICINE-
CiteScore
0.60
自引率
0.00%
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