Persistent activity and therapeutic efficacy of Delcid® 7.5 against scab mites (Psoroptes ovis) in sheep

S. Engashev, E. Engasheva, V. Kolesnikov, B. Bagamaev, R. J. Ustarov
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Abstract

The purpose of the research is to study persistent activity and therapeutic efficacy of Delcid® 7.5 against scab mites Psoroptes ovis in sheep.Materials and methods. The studies were performed in the Bukhty peasant farm enterprise in November 2021 on the Kizlyarsky District winter pastures in the Republic of Dagestan. Three groups of sheep were formed, of which two groups (second and third) had a confirmed clinical diagnosis of psoroptic mange (P. ovis) and one group (first) was free from scab mites. Sheep from the first and second groups were treated with Delcid at a dose of 10 ml of the drug per animal. After 10 days, sheep from the second group were treated with the drug repeatedly at the same dose. Sheep from the first and second groups were treated with the drug applied on dry and intact skin of the back along the spine using the drop method. The third control (infected) group of animals was not treated. All experimental groups of sheep were kept in a common flock. The Delcid persistent activity and thera-peutic efficacy were evaluated by clinical examination and microscopy of the skin for P. ovis mites before the experiment started and at 1, 3, 7, 10, 14, 21, 25 and 30 days after treatment in the first group and at 1, 3, 7, 11, 13, 17, 20, 24, 31, 35 and 40 days in the second and third groups of sheep.Results and discussion. It was found that Delcid 7.5 showed persistent activity in sheep against psoroptic mange pathogens for 21 days after a single treatment at a dose of 10 ml per animal. Delcid acaricidal effect after double treatment against P. ovis was 31 days.
Delcid®7.5对绵羊疥疮螨(Psoroptes ovis)的持续活性和治疗效果
本研究的目的是研究Delcid®7.5对绵羊疥疮螨的持续活性和治疗效果。材料和方法。研究于2021年11月在达吉斯坦共和国基兹利亚尔斯基区冬季牧场的Bukhty农民农场企业进行。实验分为三组,其中两组(第二组和第三组)临床确诊为羊皮癣(P. ovis),一组(第一组)无痂螨。第一组和第二组的绵羊以每只10毫升的剂量接受Delcid治疗。10 d后,第二组重复给予相同剂量的药物。第一组和第二组羊采用滴药法将药物沿脊柱滴在干燥完整的背部皮肤上。第三组对照(感染)动物未接受治疗。所有实验组的羊被饲养在一个共同的羊群中。在实验开始前和治疗后第1、3、7、10、14、21、25和30天,第2和3组分别在第1、3、7、11、13、17、20、24、31、35和40天,通过临床检查和皮肤镜检评估Delcid的持久活性和治疗效果。结果和讨论。研究发现,Delcid 7.5在每只羊10毫升的单次处理后,对绵羊的皮肤管理病原体表现出持续21天的活性。双重处理后的Delcid杀螨效果为31 d。
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