Structural properties of food proteins underlying stability or susceptibility to human gastrointestinal digestion

IF 8.9 1区 农林科学 Q1 FOOD SCIENCE & TECHNOLOGY
Gianluca Picariello , Francesco Siano , Luigia Di Stasio , Gianfranco Mamone , Francesco Addeo , Pasquale Ferranti
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引用次数: 5

Abstract

Is any specific structural trait that makes food proteins resistant or sensitive to proteolytic degradation in the gastrointestinal tract? In principle, elements at various hierarchical levels of protein structure may confer stability or susceptibility to hydrolysis. However, based on a critical revision of the recent literature, we emphasize the impossibility of providing absolute answers because protein digestion is affected by a complex series of factors ascribable to the food micro-/macrostructure and the intricacy of human digestion. Taking into consideration the uncertainty associated with the current in vitro models of food digestion/absorption and the capability offered by recent analytical advancements, we emphasize the need for suitable in vivo readouts for improving the comprehension of the fate of dietary proteins in our body and their effects on human health.

食物蛋白质的结构特性及其对人体胃肠道消化的稳定性和易感性
是否有任何特定的结构特征使食物蛋白质对胃肠道中的蛋白质水解降解具有抗性或敏感性?原则上,在不同层次的蛋白质结构的元素可能赋予稳定性或敏感性水解。然而,基于对最近文献的批判性修订,我们强调提供绝对答案是不可能的,因为蛋白质消化受到归因于食物微观/宏观结构和人类消化复杂性的一系列复杂因素的影响。考虑到目前体外食物消化/吸收模型的不确定性,以及最近的分析进展所提供的能力,我们强调需要合适的体内读数,以提高对饮食蛋白质在我们体内的命运及其对人类健康的影响的理解。
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来源期刊
Current Opinion in Food Science
Current Opinion in Food Science Agricultural and Biological Sciences-Food Science
CiteScore
18.40
自引率
4.00%
发文量
157
审稿时长
92 days
期刊介绍: Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts. Key Features: Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science. Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications. Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.
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