Standardization of In Vitro Studies for Plasmonic Photothermal therapy

IF 4.8 Q2 NANOSCIENCE & NANOTECHNOLOGY

ACS Nanoscience Au Pub Date : 2023-07-17 DOI:10.1021/acsnanoscienceau.3c00011

Helena Villuendas, Clara Vilches* and Romain Quidant*,

引用次数: 1

Abstract

Lack of standardization is a systematic problem that impacts nanomedicine by challenging data comparison from different studies. Translation from preclinical to clinical stages indeed requires reproducible data that can be easily accessed and compared. In this work, we propose a series of experimental standards for in vitro plasmonic photothermal therapy (PPTT). This best practice guide covers the five main aspects of PPTT studies in vitro: nanomaterials, biological samples, pre-, during, and postirradiation characterization. We are confident that such standardization of experimental protocols and reported data will benefit the development of PPTT as a transversal therapy.

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等离子体光热治疗体外研究的标准化

缺乏标准化是一个系统性问题，它通过挑战不同研究的数据比较来影响纳米医学。从临床前阶段到临床阶段的转换确实需要易于访问和比较的可重复数据。在这项工作中，我们提出了一系列的实验标准的体外等离子体光热治疗(PPTT)。本最佳实践指南涵盖了体外PPTT研究的五个主要方面:纳米材料，生物样品，辐射前，辐射期间和辐射后表征。我们相信，这种实验方案和报告数据的标准化将有利于PPTT作为一种横向治疗的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Nanoscience Au 材料科学、纳米科学-

CiteScore

4.20

自引率

0.00%

发文量

期刊介绍： ACS Nanoscience Au is an open access journal that publishes original fundamental and applied research on nanoscience and nanotechnology research at the interfaces of chemistry biology medicine materials science physics and engineering.The journal publishes short letters comprehensive articles reviews and perspectives on all aspects of nanoscience and nanotechnology:synthesis assembly characterization theory modeling and simulation of nanostructures nanomaterials and nanoscale devicesdesign fabrication and applications of organic inorganic polymer hybrid and biological nanostructuresexperimental and theoretical studies of nanoscale chemical physical and biological phenomenamethods and tools for nanoscience and nanotechnologyself- and directed-assemblyzero- one- and two-dimensional materialsnanostructures and nano-engineered devices with advanced performancenanobiotechnologynanomedicine and nanotoxicologyACS Nanoscience Au also publishes original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials engineering physics bioscience and chemistry into important applications of nanomaterials.