In Vitro Comparative Analysis of Antibacterial Activity of Different Fractions of Corchorus capsularis and Corchorus olitorius Leaves Extracts

Riad Raihan Abir, Mafruha Marjia, Nadira Naznin Rakhi, Otun Saha, M. Hossain, M. Rahaman
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引用次数: 5

Abstract

Antibiotic resistance is of prime public health concern worldwide and especially for countries like Bangladesh having the high prevalence of antibiotic resistance with high selective pressure leading to the development of antibiotic resistance due to misuse and/or overuse of antibiotics. The recent reports of emerging antibiotic resistance genes, especially the genes conferring the resistance to the last resort antibiotics such as carbapenems has made the scenario even worse for Bangladesh1-2. So, it is high time we should search for alternative options to the existing antibiotics. And bioactive molecules from different medicinal herbs and plants have already gained attention as an alternative regimen and already been reported to yield better results than antimicrobials from combinatorial chemistry and synthetic procedures3. Different herbal preparations have also been being used for treatment of ailments since ancient times4.
荚膜corcorus不同部位与山竹corcorus叶片提取物抑菌活性的体外比较分析
抗生素耐药性是世界范围内主要的公共卫生问题,特别是对于像孟加拉国这样抗生素耐药性高发的国家,由于抗生素的滥用和/或过度使用,高选择压力导致抗生素耐药性的发展。最近关于新出现的抗生素耐药基因的报道,特别是对碳青霉烯类等最后手段的抗生素具有耐药性的基因,使孟加拉国的情况更加糟糕。因此,是时候寻找现有抗生素的替代方案了。从不同的草药和植物中提取的生物活性分子作为一种替代疗法已经引起了人们的注意,并且已经有报道称其比通过组合化学和合成方法获得的抗菌剂产生更好的效果。自古以来,不同的草药制剂也被用于治疗疾病。
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