Valoración de la prueba de ADN en las identificaciones a gran escala de personas desaparecidas

Q3 Medicine
Lourdes Prieto , Yarimar Ruiz , Elías Hernandis , Ángel Carracedo
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引用次数: 4

Abstract

The evaluation of the DNA test in massive identification cases requires the use of Bayes' Theorem to estimate the probability of identification from a priori data together with probabilities obtained from the DNA test itself. To apply it, one needs to specify the prior probabilities of the hypotheses. An interdisciplinary team and an identification coordinator are key stakeholders in this process. The statistical approach can be complex, but there exists validated non-commercial software, such as Familias, which aid in estimating the likelihood ratios of the DNA test for the given hypotheses. Next, the posterior probabilities in massive identification events can be estimated using the one-to-one, PM-driven, AM-driven or Global approaches published recently by Kling et al. Which are discussed in this article. The Identification Coordinator has a key role in formulating the hypotheses of the case, in establishing the prior probabilities, the identification threshold and in consolidating the integrated identification report together with the multidisciplinary team through the reconciliation of the case.

dna测试在大规模失踪人员身份鉴定中的价值
在大量鉴定案例中对DNA检测进行评估,需要利用贝叶斯定理,结合DNA检测本身得到的概率,从先验数据中估计鉴定的概率。要应用它,需要指定假设的先验概率。在这个过程中,一个跨学科的团队和一个鉴定协调员是关键的利益相关者。统计方法可能是复杂的,但是存在有效的非商业软件,例如Familias,它可以帮助估计给定假设的DNA测试的似然比。接下来,可以使用Kling等人最近发表的一对一、pm驱动、am驱动或Global方法来估计大规模识别事件的后验概率。本文将对此进行讨论。鉴定协调员在制定案件假设、确定先验概率、鉴定阈值以及通过协调案件与多学科小组一起巩固综合鉴定报告方面发挥关键作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Revista Espanola de Medicina Legal
Revista Espanola de Medicina Legal Medicine-Pathology and Forensic Medicine
CiteScore
1.90
自引率
0.00%
发文量
27
审稿时长
41 days
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