Characteristics of maternal cardiac disease and pregnancy outcomes: results from a 4-year observational cohort survey in Central Vietnam

IF 0.4 4区医学 Q4 OBSTETRICS & GYNECOLOGY

Clinical and experimental obstetrics & gynecology Pub Date : 2022-01-12 DOI:10.31083/j.ceog4901013

M. Le, Minh Thang Tran, T. Nguyen, D. T. Tran, Quang Vinh Truong, Quoc Huy Vu Nguyen

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引用次数: 0

Abstract

Background: Pregnant womenwith cardiac diseases present a challenge for both obstetricians and cardiologists, especially in developing countries with limited medical resources. This study aimed to determine the clinical features and pregnancy outcomes of pregnant women with cardiac diseases in Vietnam. Methods: In this patient registry descriptive study, pregnant women with heart disease, admitted to the Department of Obstetrics and Gynecology, Hue Central Hospital, Vietnam, between January 2017 and December 2020, were recruited. Pregnant women were classified into the high-risk group if at least one of the following risk clinical features was present: (1) left ventricular ejection fraction (EF)<50%, and (2) New York Heart Association—NYHA classification—NYHA class>II or cyanosis, or (3) left heart obstruction; patients without these risk conditions were categorized into the low-risk group. Results: A total of 134 pregnant women were included, with a mean age of 27.8 ± 4.8 years old; 32.1% had mitral valve disease, 23.9% had rhythm disorders, 15.7% had congenital heart disease, 9.0% had aortic valve disease, and 3.0% had both mitral and aortic valve disease. Maternal complications during pregnancy included heart failure (37.3%), irregular heart rhythm (35.8%), thrombosis (0.7%), and valve blockage (0.7%). A total of 66.7% of the high-risk patients underwent cesarean section, 22.2% with therapeutic abortion, and 11.1% with miscarriage. The frequency of gestational age over 35 weeks in the high-risk and low-risk groups were 55.6% and 92.8%, respectively (Odds ratios = 0.097, 95% Confidence Interval: 0.02–0.43, p < 0.05). The mean birth weight in the high-risk and low-risk groups was 2800.0 ± 438.2 and 2988.4± 390.6 g, p> 0.05, respectively. Conclusions: Cardiovascular disorders in pregnant women have a higher rate of complications that affect mother and fetus. Risk stratification plays an important role in management during pregnancy and is essential to improve the outcomes in developing countries with limited medical

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产妇心脏病和妊娠结局的特征:来自越南中部一项为期4年的观察性队列调查的结果

背景：患有心脏病的孕妇对产科医生和心脏病专家来说都是一个挑战，尤其是在医疗资源有限的发展中国家。本研究旨在确定越南患有心脏病的孕妇的临床特征和妊娠结局。方法：在这项患者登记描述性研究中，招募了2017年1月至2020年12月期间入住越南顺化中央医院妇产科的患有心脏病的孕妇。如果至少存在以下一种危险临床特征，孕妇被分为高危组：（1）左心室射血分数（EF）II或发绀，或（3）左心梗阻；没有这些危险情况的患者被分为低危险组。结果：共纳入134名孕妇，平均年龄27.8±4.8岁；32.1%患有二尖瓣疾病，23.9%患有心律失常，15.7%患有先天性心脏病，9.0%患有主动脉瓣疾病，3.0%同时患有二尖瓣和主动脉瓣疾病。妊娠期间的母亲并发症包括心力衰竭（37.3%）、心律失常（35.8%）、血栓形成（0.7%）和瓣膜堵塞（0.7%）。共有66.7%的高危患者接受了剖宫产，22.2%接受了治疗性流产，11.1%流产。高风险组和低风险组的胎龄超过35周的频率分别为55.6%和92.8%（比值比=0.097，95%置信区间：0.02–0.43，p<0.05）。高风险组的平均出生体重分别为2800.0±438.2和2988.4±390.6 g，p>0.05。结论：孕妇心血管疾病对母亲和胎儿的并发症发生率较高。风险分层在妊娠期管理中发挥着重要作用，对于改善医疗条件有限的发展中国家的预后至关重要

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来源期刊

Clinical and experimental obstetrics & gynecology 医学-妇产科学

CiteScore

0.50

自引率

0.00%

发文量

241

审稿时长

1 months

期刊介绍： CEOG is an international, peer-reviewed, open access journal. CEOG covers all aspects of Obstetrics and Gynecology, including obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine. All submissions of cutting-edge advances of medical research in the area of women''s health worldwide are encouraged.