Dorsal midbrain squamous cell carcinoma: Case report and review of literature

Q2 Medicine

Medical Journal Armed Forces India Pub Date : 2024-12-01 DOI:10.1016/j.mjafi.2023.01.005

Subir Dey , Abhinav Debanath

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引用次数: 0

Abstract

Intracranial epidermoid cyst (EC) is a slow-growing, benign lesion that rarely undergoes a malignant transformation. When it does occur, the clinical course is aggressive. Certain radiological criteria may give a clue to diagnosis and help in deciding the appropriate course of action as well as prognostication. Surgical excision along with adjuvant radiotherapy is the treatment of choice; however, the overall prognosis is poor as complete excision is seldom possible. We present a rare case of malignant transformation of an intracranial EC without previous history of surgery. Subtotal excision of the lesion was possible, with post-operative histopathological examination revealing squamous cell carcinoma. The patient was discharged from the hospital with no fresh deficits. She was, however, re-admitted on day 36 with features of raised intracranial pressure, for which she underwent cerebrospinal fluid diversion. She underwent intensity-modulated radiation therapy later on.

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中脑背侧鳞状细胞癌病例报告及文献复习

颅内表皮样囊肿（EC）是一种生长缓慢的良性病变，很少发生恶性转化。当它确实发生时，临床过程是侵略性的。某些放射学标准可以为诊断提供线索，并有助于决定适当的治疗方案和预后。手术切除加辅助放疗是治疗的首选；然而，由于完全切除很少可能，整体预后较差。我们提出一个罕见的病例恶性转化颅内EC没有既往的手术史。病灶大部切除是可能的，术后组织病理学检查显示鳞状细胞癌。病人出院时没有新的缺陷。然而，她在第36天再次入院，颅内压升高，为此她接受了脑脊液分流。后来她接受了调强放射治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medical Journal Armed Forces India Medicine-Medicine (all)

CiteScore

3.40

自引率

0.00%

发文量

206

期刊介绍： This journal was conceived in 1945 as the Journal of Indian Army Medical Corps. Col DR Thapar was the first Editor who published it on behalf of Lt. Gen Gordon Wilson, the then Director of Medical Services in India. Over the years the journal has achieved various milestones. Presently it is published in Vancouver style, printed on offset, and has a distribution exceeding 5000 per issue. It is published in January, April, July and October each year.