Long-Term Results of Excimer Laser Surface Ablation with Smoothing for High Myopia

P. Vinciguerra, Ingrid Torres, Adriana Sergio, E. Legrottaglie, F. Camesasca
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Abstract

Purpose: To evaluate long-term refractive, aberrometric and anatomical results of surface ablation plus corneal PTK-style smoothing for myopia greater than –7.00 D. Methods: One-hundred-and-fourteen eyes of 69 patients (mean age: 37.7 ± 8.3 years) underwent PRK with the NIDEK EC-5000 excimer laser (NIDEK Co. Ltd., Gamagori, Japan) using multiple optical zones ranging in diameter from 4.89 mm to 7.0 mm, and transition zones (TZ) that were at least 3 mm wider than the optical zones (OZ). A cross-cylinder technique was used for treating astigmatism greater than 0.50 D. All eyes underwent a phototherapeutic keratectomy (PTK) smoothing technique using masking fluid. The Student’s t-test was used to determine a statistically significant change after surgery. A p value less than 0.05 was considered statistically significant. Results: Preoperative corrected distance visual acuity (CDVA) was 0.88 ± 0.16 with –9.53 ± 1.18 D cycloplegic spherical equivalent (SE). Preoperative corneal pachymetry was 560.4 ± 30.1 µ. Three years after surgery uncorrected visual acuity (UCVA) was 0.79 ± 0.26, CDVA was 0.92 ± 0.19 with –0.56 ± 0.90 D SE. Mean corneal haze was highest 1 month after surgery (0.58 ± 0.35), then progressively decreased to 0.11 ± 0.32 by 3 months postoperatively. Following year one, refraction and corneal curvature remained stable. There were no cases of keractasia to date. There was no hyperopic induction due to PTK. Two eyes required retreatment due to undercorrection. Total wavefront error did not change significantly, while astigmatism decreased and coma increased (both with p< 0.001). Conclusion: Surface ablation for the treatment of high myopia using PTK smoothing with a masking fluid was safe and effective. Wide optical and transition zones prevented induction of spherical aberration and the incorporation of the smoothing technique created a regular corneal surface with regular healing and trace to no haze after surgery.
准分子激光表面平滑消融治疗高度近视的远期疗效
目的:评价表面消融加角膜PTK式平滑术治疗-7.00D以上近视的长期屈光、像差和解剖结果。方法:用NIDEK EC-5000准分子激光(NIDEK Co。有限公司,Gamagori,Japan),使用直径范围从4.89毫米到7.0毫米的多个光学区域,以及比光学区域(OZ)宽至少3毫米的过渡区域(TZ)。使用交叉柱体技术治疗大于0.50D的散光。所有眼睛都接受了使用掩蔽液的光治疗性角膜切除术(PTK)平滑技术。Student t检验用于确定手术后的统计学显著变化。p值小于0.05被认为具有统计学意义。结果:术前矫正远距视力(CDVA)为0.88±0.16,睫状肌麻痹球当量为-9.53±1.18D。术前角膜厚度为560.4±30.1µ。术后3年裸眼视力(UCVA)为0.79±0.26,CDVA为0.92±0.19,D SE为-0.56±0.90。术后1个月平均角膜雾度最高(0.58±0.35),术后3个月逐渐降至0.11±0.32。第一年之后,屈光度和角膜曲率保持稳定。到目前为止,还没有出现keractasia的病例。PTK没有引起远视。由于矫正不足,两只眼睛需要重新矫正。总波前误差无明显变化,散光减少,昏迷增加(均p<0.001)。宽的光学区和过渡区防止了球面像差的诱导,平滑技术的结合创造了一个规则的角膜表面,有规则的愈合,手术后几乎没有雾翳。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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