Emerging Trends in the Application of Green Synthesized Biocompatible ZnO Nanoparticles for Translational Paradigm in Cancer Therapy

Journal of nanotheranostics Pub Date : 2023-07-01 DOI:10.3390/jnt4030012

Shaikh Sheeran Naser, Basab Ghosh, Faizan Zarreen Simnani, Dibyangshee Singh, Anmol Choudhury, A. Nandi, Adrija Sinha, E. Jha, P. Panda, M. Suar, Suresh K. Verma

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引用次数: 6

Abstract

Zinc oxide nanomaterials have been the cynosure of this decade because of their immense potential in different biomedical applications. It includes their usage in the prognosis and treatment of different infectious and cellular diseases, owing to their peculiar physiochemical properties such as variable shape, size, and surface charge etc. Increasing demand and usage of the ZnO nanomaterials raise concerns about their cellular and molecular toxicity and their biocompatibility with human cells. This review comprehensively details their physiochemical properties for usage in biomedical applications. Furthermore, the toxicological concerns of ZnO nanomaterials with different types of cellular systems have been reviewed. Moreover, the biomedical and biocompatible efficacy of ZnO nanomaterials for cancer specific pathways has been discussed. This review offers insights into the current scenario of ZnO nanomaterials usage and signifies their potential future extension usage on different types of biomedical and environmental applications.

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绿色合成生物相容性ZnO纳米粒子在癌症治疗中应用的新趋势

氧化锌纳米材料因其在不同生物医学应用中的巨大潜力而成为这十年的焦点。由于其独特的物理化学性质，如形状、大小和表面电荷等，ZnO纳米材料可用于不同感染性和细胞性疾病的预后和治疗。对ZnO纳米材料的需求和使用的增加引起了人们对其细胞和分子毒性及其与人细胞的生物相容性的担忧。本文综述了它们在生物医学应用中的理化性质。此外，还对具有不同类型细胞系统的ZnO纳米材料的毒理学问题进行了综述。此外，还讨论了ZnO纳米材料对癌症特异性途径的生物医学和生物相容性功效。这篇综述深入了解了ZnO纳米材料的当前使用情况，并表明了它们在不同类型的生物医学和环境应用中的潜在未来扩展用途。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of nanotheranostics

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