Melatoninergic Antidepressant in Post-Stroke Depression Therapy

V. Kuznetsov
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Abstract

This paper presents the results of the effects of Melitor (25 mg during two months) on the psychic-emotional state, cerebral hemodynamic and bioelectrical activity of the brain in 30 patients (average age 66.2 ± 3.2 years) with ischemic post-stroke depression. It has been found that this drug possesses a multimodal action which is characterized by the decrease of the level of depression, widening of the range of social-environmental activity, improvement of the cerebral blood circulation and harmonization of the brain electrogenesis. In the patients with right versus left hemisphere stroke, the effect of Melitor on the functional state of the brain was more pronounced. Based on the results obtained in our study, we can recommend Melitor to use it in complex scheme of rehabilitation care of patients of the given nosological category.
褪黑素抗抑郁药在脑卒中后抑郁治疗中的应用
本文对30例缺血性脑卒中后抑郁患者(平均年龄66.2±3.2岁)给予美立妥(25 mg / 2个月)治疗,观察其对精神情绪状态、脑血流动力学和脑生物电活动的影响。研究发现,该药具有降低抑郁水平、扩大社会环境活动范围、改善脑血液循环和协调脑电的多模态作用。在右脑和左脑卒中患者中,美立妥对大脑功能状态的影响更为明显。根据我们的研究结果,我们可以推荐美立妥在特定疾病分类患者的复杂康复护理方案中使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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