Female fertility under the impact of COVID-19 pandemic: a narrative review

IF 4.5 2区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Expert Reviews in Molecular Medicine Pub Date : 2021-11-02 DOI:10.1017/erm.2021.19

Meng Wang, Bo Zhang, L. Jin

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引用次数: 2

Abstract

Abstract Coronavirus disease 2019 (COVID-19) is a serious respiratory disease mediated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The worldwide spread of COVID-19 has caused millions of confirmed cases and morbidity, and the crisis has greatly affected global economy and daily life and changed our attitudes towards life. The reproductive system, as a potential target, is at a high risk of SARS-CoV-2 infection, and females are more vulnerable to viral infection compared with males. Therefore, female fertility and associated reproductive health care in the COVID-19 era need more attention. This review summarises the mechanism of SARS-CoV-2 infection in the female reproductive system and discusses the impact of the COVID-19 crisis on female fertility. Studies have proven that COVID-19 might affect female fertility and interfere with assisted reproductive technology procedures. The side effects of vaccines against the virus on ovarian reserve and pregnancy have not yet been well investigated. In the future, the female fertility after SARS-CoV-2 infection and vaccination needs more attention because of the uncertainty of COVID-19.

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新冠肺炎大流行影响下的女性生育率：叙述性综述

摘要2019冠状病毒病（新冠肺炎）是一种由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染介导的严重呼吸道疾病。新冠肺炎在全球范围内的传播已造成数百万确诊病例和发病率，这场危机极大地影响了全球经济和日常生活，改变了我们的生活态度。生殖系统作为一个潜在的目标，感染严重急性呼吸系统综合征冠状病毒2型的风险很高，与男性相比，女性更容易受到病毒感染。因此，新冠肺炎时代的女性生育率和相关生殖健康护理需要更多关注。这篇综述总结了女性生殖系统中SARS-CoV-2感染的机制，并讨论了新冠肺炎危机对女性生育能力的影响。研究证明，新冠肺炎可能影响女性生育能力并干扰辅助生殖技术程序。针对该病毒的疫苗对卵巢储备和妊娠的副作用尚未得到很好的研究。未来，由于新冠肺炎的不确定性，女性在感染和接种SARS-CoV-2后的生育能力需要更多关注。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Reviews in Molecular Medicine BIOCHEMISTRY & MOLECULAR BIOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL

CiteScore

7.40

自引率

1.60%

发文量

期刊介绍： Expert Reviews in Molecular Medicine is an innovative online journal featuring authoritative and timely Reviews covering gene therapy, immunotherapeutics, drug design, vaccines, genetic testing, pathogenesis, microbiology, genomics, molecular epidemiology and diagnostic techniques. We especially welcome reviews on translational aspects of molecular medicine, particularly those related to the application of new understanding of the molecular basis of disease to experimental medicine and clinical practice.