Variability of dental abnormalities according to the timing of anticancer therapy: A report of two cases

IF 0.6 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal Pub Date : 2022-08-01 DOI:10.1016/j.pdj.2022.03.001

Gimin Kim, Jaesik Lee

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引用次数: 0

Abstract

Background

Current multimodality therapies have increased the survival of patients with childhood cancer. However, these therapies increase the risk of dental complications.

Case report

The first case was a 7-year-old girl who was diagnosed with leukemia at around 8 months of age and received anticancer therapy for about 1 year. The second case was an 8-year-old boy who was diagnosed with leukemia at around the age of 6 and received anticancer therapy for about 2 years. Based on long-term follow-up of two cases, tooth agenesis and microdontia occurs when anticancer therapy is performed at the initial stage of tooth development. However shortening roots of the affected teeth can be found when it is performed at the late stage of tooth development.

Conclusions

Early diagnosis and understanding of dental developmental defects resulting from anticancer therapy are essential for preventing tooth loss and space-related problems in the oral cavity.

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根据抗癌治疗时间变化的牙齿异常:附两例报告

目前的多模式治疗提高了儿童癌症患者的生存率。然而，这些疗法增加了牙齿并发症的风险。第一个病例是一个7岁的女孩，她在大约8个月大的时候被诊断出患有白血病，并接受了大约1年的抗癌治疗。第二个病例是一个8岁的男孩，他在6岁左右被诊断出患有白血病，接受了大约2年的抗癌治疗。通过对2例患者的长期随访，发现在牙齿发育初期进行抗癌治疗，出现了牙齿发育不全和小牙畸形。然而，当在牙齿发育的后期进行时，可以发现受影响牙齿的根变短。结论早期诊断和了解肿瘤治疗引起的牙齿发育缺陷，对预防牙齿脱落和与口腔空间相关的问题至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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