Uchechukwu S. Ezealigo , Blessing N. Ezealigo , Samson O. Aisida , Fabian I. Ezema
{"title":"Iron oxide nanoparticles in biological systems: Antibacterial and toxicology perspective","authors":"Uchechukwu S. Ezealigo , Blessing N. Ezealigo , Samson O. Aisida , Fabian I. Ezema","doi":"10.1016/j.jciso.2021.100027","DOIUrl":null,"url":null,"abstract":"<div><p>There has been an increasing number of studies in magnetic nanoparticles with auspicious applications in medicine. Among the oxides of magnetic nanoparticles, iron oxide has emerged as an indispensable tool in nanotechnology, particularly bio-nanotechnology. This is attributed to its exceptional properties such as size, shape, magnetism, and biocompatibility. In this review, iron oxide nanoparticles were exploited in different model organisms ranging from prokaryotes to eukaryotes, elucidating their cellular functions relative to their antibacterial activity, drug delivery, and toxicity.</p></div>","PeriodicalId":73541,"journal":{"name":"JCIS open","volume":"4 ","pages":"Article 100027"},"PeriodicalIF":0.0000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666934X2100026X/pdfft?md5=f5ba7434b24b23805ad55cd1343e6832&pid=1-s2.0-S2666934X2100026X-main.pdf","citationCount":"38","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JCIS open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666934X2100026X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Materials Science","Score":null,"Total":0}
引用次数: 38
Abstract
There has been an increasing number of studies in magnetic nanoparticles with auspicious applications in medicine. Among the oxides of magnetic nanoparticles, iron oxide has emerged as an indispensable tool in nanotechnology, particularly bio-nanotechnology. This is attributed to its exceptional properties such as size, shape, magnetism, and biocompatibility. In this review, iron oxide nanoparticles were exploited in different model organisms ranging from prokaryotes to eukaryotes, elucidating their cellular functions relative to their antibacterial activity, drug delivery, and toxicity.