Clinic and diagnostics of house dust mite allergy

Q3 Medicine

Allergo Journal International Pub Date : 2022-11-24 DOI:10.1007/s40629-022-00232-7

Randolf Brehler

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引用次数: 3

Abstract

Summary

House dust mite allergens are common triggers for allergic rhinoconjunctivitis and allergic asthma; they can aggravate atopic dermatitis and rarely lead to anaphylactic reactions due to dust mite allergens in food. Typical symptoms are nasal obstruction, sneezing, and irritation, and more often than in pollen allergy, allergic asthma also develops. The symptomatology exists in principle throughout the year with maximum complaints in autumn and winter. Of particular importance are sleep disturbances due to nasal obstruction, which lead to restrictions in the quality of life and performance of affected patients. Sensitization can be proven by skin tests and detection of serum allergen-specific IgE antibodies; proof of allergy is achieved by nasal or conjunctival provocation tests. The diagnosis of local allergic rhinitis can only be made by provocation or by determination of allergen-specific IgE antibodies in nasal secretions. The quality of the allergen extract used is essential for all tests; it must contain the allergens to which a patient is sensitized. The concentration of Der p 23 in house dust mite extracts is particularly critical.

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屋尘螨过敏的临床与诊断

SummaryHouse尘螨过敏原是过敏性鼻结膜炎和过敏性哮喘的常见诱因；它们会加重特应性皮炎，很少因食物中的尘螨过敏原而引起过敏反应。典型的症状是鼻塞、打喷嚏和刺激，而且比花粉过敏更常见的是，还会出现过敏性哮喘。症状学原则上全年都存在，秋季和冬季症状最多。特别重要的是鼻阻塞引起的睡眠障碍，这会限制受影响患者的生活质量和表现。可以通过皮肤测试和血清过敏原特异性IgE抗体的检测来证明致敏作用；通过鼻腔或结膜刺激试验来证明过敏。局部过敏性鼻炎的诊断只能通过激发或通过测定鼻腔分泌物中的过敏原特异性IgE抗体来进行。所用过敏原提取物的质量对所有测试至关重要；它必须含有患者对其敏感的过敏原。Der p 23在屋尘螨提取物中的浓度是特别关键的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Allergo Journal International Medicine-Immunology and Allergy

CiteScore

4.60

自引率

0.00%

发文量

期刊介绍： Allergo Journal International is the official Journal of the German Society for Applied Allergology (AeDA) and the Austrian Society for Allergology and Immunology (ÖGAI). The journal is a forum for the communication and exchange of ideas concerning the various aspects of allergy (including related fields such as clinical immunology and environmental medicine) and promotes German allergy research in an international context. The aim of Allergo Journal International is to provide state of the art information for all medical and scientific disciplines that deal with allergic, immunological and environmental diseases. Allergo Journal International publishes original articles, reviews, short communications, case reports, and letters to the editor. The articles cover topics such as allergic, immunological and environmental diseases, the latest developments in diagnosis and therapy as well as current research work concerning antigens and allergens and aspects related to occupational and environmental medicine. In addition, it publishes clinical guidelines and position papers approved by expert panels of the German, Austrian and Swiss Allergy Societies. All submissions are reviewed in single-blind fashion by at least two reviewers. Originally, the journal started as a German journal called Allergo Journal back in 1992. Throughout the years, English articles amounted to a considerable portion in Allergo Journal. This was one of the reasons to extract the scientific content and publish it in a separate journal. Hence, Allergo Journal International was born and now is the international continuation of the original German journal. Nowadays, all original content is published in Allergo Journal International first. Later, selected manuscripts will be translated and published in German and included in Allergo Journal.