Acupuncture for fibromyalgia: An evidence map 针灸治疗纤维肌痛:证据图

Abstract

Objective

The body of research on acupuncture as a treatment strategy for fibromyalgia (FM) is steadily growing. This evidence map identifies, describes, and summarizes the current status of studies conducted to evaluate the efficacy of acupuncture for FM, identify research gaps, and provide information that could guide the design of future studies.

Methods

Seven electronic databases–Cochrane Library, PubMed, Embase, China Biomedical Literature Database, VIP, Wanfang Database, and Chinese National Knowledge Infrastructure–were searched for relevant articles on acupuncture for FM. The search period was from the dates of inception of the databases to December 19, 2022. Original clinical studies and systematic reviews on the use of acupuncture-related modalities for the treatment of FM were included. The basic information, quality assessments, and evidence maps of the included studies are presented as charts and bubble plots. The quality assessment tools used for evaluating the different types of studies included in the present study were Cochrane Collaboration's tool, Canadian Institute of Health Economics quality appraisal tool, and A MeaSurement Tool to Assess systematic Reviews 2.

Results

Fifty studies were included in this study. Of these, 39 (78.00%) were randomized controlled trials (RCTs), 6 (12.0%) were case series, and 5 (10.0%) were systematic reviews. The included studies focused on manual acupuncture and conventional treatment in the treatment and control groups, respectively. The outcomes analyzed in the RCTs included pain (94.9%), sleep quality (46.2%), depression (46.2%), physical function (46.2%), stiffness (35.9%), well-being (35.9%), work status (35.9%), anxiety (33.3%), fatigue (33.3%), quality of life (17.9%), and overall effective rate (10.3%). The methodological quality of most of the studies was low or critically low regardless of the study design. In most studies, the therapeutic effect of acupuncture was significantly superior to that of the comparator.

Conclusion

This evidence map suggests that acupuncture-related modalities may be promising options for FM management. However, various studies on this topic have a high risk of bias or are of low quality. Further evidence-based research should be conducted to rigorously examine the efficacy of acupuncture for FM and promote generalizability of the findings.