The Genetics and Epigenetics of Sex Change in Fish.

IF 8.7 1区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Annual Review of Animal Biosciences Pub Date : 2020-02-15 DOI:10.1146/annurev-animal-021419-083634

O. Ortega-Recalde, A. Goikoetxea, T. Hore, E. Todd, N. Gemmell

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引用次数: 49

Abstract

Fish show extraordinary sexual plasticity, changing sex naturally as part of their life cycle or reversing sex because of environmental stressors. This plasticity shows that sexual fate is not an irreversible process but the result of an ongoing tug-of-war for supremacy between male and female signaling networks. The behavioral, gonadal, and morphological changes involved in this process are well described, yet the molecular events that underpin those changes remain poorly understood. Epigenetic modifications emerge as a critical link between environmental stimuli, the onset of sex change, and subsequent maintenance of sexual phenotype. Here we synthesize current knowledge of sex change, focusing on the genetic and epigenetic processes that are likely involved in the initiation and regulation of sex change. We anticipate that better understanding of sex change in fish will shed new light on sex determination and development in vertebrates and on how environmental perturbations affect sexual fate. Expected final online publication date for the Annual Review of Animal Biosciences, Volume 8 is February 15, 2020. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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鱼类性别变化的遗传学和表观遗传学。

鱼类表现出非凡的性可塑性，作为生命周期的一部分，它们会自然地改变性别，也会因为环境压力而改变性别。这种可塑性表明，性别命运不是一个不可逆转的过程，而是雄性和雌性信号网络之间争夺霸权的持续拉锯战的结果。在这一过程中所涉及的行为、性腺和形态变化已经被很好地描述了，然而支撑这些变化的分子事件仍然知之甚少。表观遗传修饰是环境刺激、性别变化的发生和随后的性表型维持之间的关键联系。在这里，我们综合了目前关于性别变化的知识，重点关注可能涉及性别变化的启动和调节的遗传和表观遗传过程。我们预计，对鱼类性别变化的更好理解将为脊椎动物的性别决定和发育以及环境扰动如何影响性别命运提供新的线索。《动物生物科学年度评论》第8卷的最终在线出版日期预计为2020年2月15日。修订后的估计数请参阅http://www.annualreviews.org/page/journal/pubdates。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual Review of Animal Biosciences BIOTECHNOLOGY & APPLIED MICROBIOLOGY-ZOOLOGY

CiteScore

21.30

自引率

0.80%

发文量

期刊介绍： The Annual Review of Animal Biosciences is primarily dedicated to the fields of biotechnology, genetics, genomics, and breeding, with a special focus on veterinary medicine. This includes veterinary pathobiology, infectious diseases and vaccine development, and conservation and zoo biology. The publication aims to address the needs of scientists studying both wild and domesticated animal species, veterinarians, conservation biologists, and geneticists.