Burden of traumatic spinal cord injury in Africa: a scoping review protocol

D. Jesuyajolu, Temitayo Ayantayo, E. Oyesiji, Sofia Bakare, Samuel Oreoluwa David, Rosola Sule, J. Daniel, Okere Madeleine, Tomiwa Olukoya, T. Osunronbi, Olaniyan Adewale, E. Morgan.
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Abstract

Trauma accounts for about 90% of spinal cord injuries worldwide. Traumatic spinal cord injury (TSCI) is recognized as a neurotrauma of global health priority due to the preventability of the injuries and the specialized and expensive medical and surgical care they necessitate. This study protocol guides the comprehensive and exhaustive review of the literature concerning the epidemiology, management and outcomes of TSCIs in Africa. This protocol follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. The search strategy was performed primarily on PubMed and OVID Embase. A secondary literature search was carried out on African Journal Online and Google Scholar. All observational studies on the prevalence/incidence, presentation, management and outcomes of TSCIs in African countries were included. The following study types were excluded: literature reviews, meta-analyses, case reports, abstract-only articles, conference proceedings, randomized control trials and letters to the editor. Our outcomes include incidence of TSCIs in Africa, mechanisms of injury, different imaging and treatment modalities offered (e.g. conservative vs. operative intervention), clinical outcomes following TSCIs in Africa and challenges regarding the management of TSCIs in African surgical centres. This study aims to provide region-specific data that will guide and inform local practices regarding TSCIs. It will also map out areas that need more research and areas amenable to intervention by global health stakeholders.
非洲创伤性脊髓损伤的负担:一项范围界定审查方案
创伤约占全世界脊髓损伤的90%。创伤性脊髓损伤(TSCI)由于其可预防性以及所需的专业且昂贵的医疗和外科护理,被公认为全球健康优先考虑的神经损伤。本研究方案指导对有关非洲TSCI流行病学、管理和结果的文献进行全面和详尽的综述。本方案遵循系统审查首选报告项目和荟萃分析方案指南。搜索策略主要在PubMed和OVID Embase上执行。在《非洲在线期刊》和谷歌学者网站上进行了二次文献检索。纳入了关于非洲国家TSCI流行率/发病率、表现、管理和结果的所有观察性研究。以下研究类型被排除在外:文献综述、荟萃分析、病例报告、仅限摘要的文章、会议记录、随机对照试验和致编辑的信件。我们的结果包括非洲TSCI的发生率、损伤机制、提供的不同成像和治疗模式(如保守干预与手术干预)、非洲TSCI后的临床结果以及非洲外科中心TSCI管理方面的挑战。本研究旨在提供特定地区的数据,以指导和告知当地有关TSCI的做法。它还将规划出需要更多研究的领域和全球卫生利益相关者可以干预的领域。
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