Isolation and Identification of Gram-Negative Bacteria from Oral Cancer Site Infections and Study of Their Antibiotic Resistance Pattern

Abstract

Cancer is currently a major global public health issue. Development of cancer cell and survival is a multifactor process that involves genetic mutation of normal cells along with physiological changes of normal body cells and the body’s defense mechanism. In Asian countries naming India, Indonesia, Philippines, Vietnam, and China more than 3 million people are expected to be diagnosed with cancer each year1. Oral cancer, globally, is the sixth most common cancer2 and is a major problem in regions where tobacco habits, in the form of chewing and/or smoking, with or without alcohol intake, are common. Cancer can take place in the anterior tongue, gingival, buccal mucosa, retromolar trigone, hard palate, salivary glands, and even tonsil glands3.