Direct Electrooxidative Selenylamination of Alkynes: Access to 3-Selenylindoles

IF 2.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Israel Journal of Chemistry Pub Date : 2023-07-24 DOI:10.1002/ijch.202300088

Balati Hasimujiang, Yong Zeng, Shifeng Zou, Kaihui Zhong, Lebin Su, Xinwei Hu, Zhixiong Ruan

引用次数: 0

Abstract

A novel metal- and oxidant-free electrooxidative selenylamination of o-aminophenacetylenes with diselenides for achieving 3-selenylindoles has been developed with moderate to excellent yield. The reaction proceeded smoothly with a broad substrate scope and highly functional group tolerance. The synthetic practicality of this innovative approach was demonstrated by its easy scalability. Moreover, mechanistic studies revealed that an in-situ generated selenium cation might be the key intermediate for the electrochemical selenocyclization process.

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炔的直接电氧化硒基层合:获得3‐硒基lindoles

研究人员开发了一种新型的无金属和氧化剂的邻氨基苯乙炔与二硒化物的电氧化硒化反应，以获得 3-硒基吲哚，该反应具有中等到极好的收率。反应进行顺利，底物范围广，官能团耐受性高。这种创新方法的易扩展性证明了其合成的实用性。此外，机理研究表明，原位生成的硒阳离子可能是电化学硒环化过程的关键中间体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Israel Journal of Chemistry 化学-化学综合

CiteScore

6.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The fledgling State of Israel began to publish its scientific activity in 1951 under the general heading of Bulletin of the Research Council of Israel, which quickly split into sections to accommodate various fields in the growing academic community. In 1963, the Bulletin ceased publication and independent journals were born, with Section A becoming the new Israel Journal of Chemistry. The Israel Journal of Chemistry is the official journal of the Israel Chemical Society. Effective from Volume 50 (2010) it is published by Wiley-VCH. The Israel Journal of Chemistry is an international and peer-reviewed publication forum for Special Issues on timely research topics in all fields of chemistry: from biochemistry through organic and inorganic chemistry to polymer, physical and theoretical chemistry, including all interdisciplinary topics. Each topical issue is edited by one or several Guest Editors and primarily contains invited Review articles. Communications and Full Papers may be published occasionally, if they fit with the quality standards of the journal. The publication language is English and the journal is published twelve times a year.