{"title":"Rex Malcolm Chaplin Dawson. 3 June 1924 — 29 March 2021","authors":"R. Irvine","doi":"10.1098/rsbm.2022.0040","DOIUrl":null,"url":null,"abstract":"Rex Dawson was a biochemist whose research interests were wide and many, but almost all of them focused on phospholipids. He was fascinated by their metabolism; by the metabolism of their catabolites; by their structure and how this impacted on the phospholipases that degrade them; by the way in which cells synthesize and transport them; by how one group of phospholipids, the phosphoinositides, contribute to cell function; by how rumen bacteria saturate the fatty acids that are part of phospholipids and how these bacteria use remarkable tricks of lipid biochemistry to maintain their membrane integrity. To all these aspects, and others, he made fundamental contributions to our knowledge that, taken together, transformed the way we understand how phospholipids govern membrane biology. As publications secretary to the Biochemical Society he helped the society through a critical time of its existence. He never ran a large research group, preferring to work with his faithful technicians and one or two visitors or students at a time. Most who met him found his quiet and modest demeanour hid an insatiable curiosity and enthusiasm for science; those who really knew his work stood in awe of his achievements.","PeriodicalId":80666,"journal":{"name":"Biographical memoirs of fellows of the Royal Society. Royal Society (Great Britain)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biographical memoirs of fellows of the Royal Society. Royal Society (Great Britain)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1098/rsbm.2022.0040","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Rex Dawson was a biochemist whose research interests were wide and many, but almost all of them focused on phospholipids. He was fascinated by their metabolism; by the metabolism of their catabolites; by their structure and how this impacted on the phospholipases that degrade them; by the way in which cells synthesize and transport them; by how one group of phospholipids, the phosphoinositides, contribute to cell function; by how rumen bacteria saturate the fatty acids that are part of phospholipids and how these bacteria use remarkable tricks of lipid biochemistry to maintain their membrane integrity. To all these aspects, and others, he made fundamental contributions to our knowledge that, taken together, transformed the way we understand how phospholipids govern membrane biology. As publications secretary to the Biochemical Society he helped the society through a critical time of its existence. He never ran a large research group, preferring to work with his faithful technicians and one or two visitors or students at a time. Most who met him found his quiet and modest demeanour hid an insatiable curiosity and enthusiasm for science; those who really knew his work stood in awe of his achievements.
Rex Dawson是一位生物化学家,他的研究兴趣广泛而广泛,但几乎所有的研究都集中在磷脂上。他们的新陈代谢使他着迷;通过其分解代谢物的代谢;通过它们的结构以及这如何影响降解它们的磷脂酶;通过细胞合成和运输它们的方式;通过一组磷脂,磷酸肌醇,如何促进细胞功能;瘤胃细菌如何饱和磷脂中的脂肪酸,以及这些细菌如何利用脂质生物化学的非凡技巧来保持其膜的完整性。在所有这些方面,以及其他方面,他对我们的知识做出了根本性的贡献,这些知识共同改变了我们理解磷脂如何控制膜生物学的方式。作为生物化学学会的出版秘书,他帮助该学会度过了其存在的关键时期。他从来没有管理过一个大型的研究小组,更喜欢一次与他忠实的技术人员和一两名访客或学生一起工作。大多数见过他的人都发现他安静谦逊的举止隐藏着对科学永不满足的好奇心和热情;那些真正了解他的工作的人对他的成就肃然起敬。