State of the art and applications in nanostructured biocatalysis

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-12-31 DOI:10.1080/13102818.2022.2054727

Fengfan Liu, Zhihao Shi, Weike Su, Jiequn Wu

引用次数: 5

Abstract

Abstract Enzymes have been widely studied for their excellent efficiency, selectivity and environmentally benign nature. However, the development of their biocatalytic applications is severely limited by the lack of stability and reusability. Nanostructured materials have been demonstrated as efficient hosts for the immobilization of enzyme due to their large surface areas as well as higher activities and long-term stability. Furthermore, nanomaterials with enzyme-like characteristics are explored as highly stable and low-cost alternatives to mimic the structures and functions of naturally occurring enzymes. This review offers an overview on the research status of enzymatic immobilization adapted from nanostructured materials and nanozymes in numerous fields, from biosensing and biocatalysis to environmental remediation, with emphasis focused on current challenges and future directions in highly selective and efficient biocatalysis.

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纳米结构生物催化的技术现状及其应用

酶因其优异的效率、选择性和环境友好性而受到广泛的研究。然而，由于缺乏稳定性和可重复使用性，其生物催化应用的发展受到严重限制。纳米结构材料由于具有较大的表面积、较高的活性和长期稳定性，已被证明是固定化酶的有效载体。此外，具有类酶特性的纳米材料被探索作为高度稳定和低成本的替代品来模拟天然存在的酶的结构和功能。本文综述了纳米结构材料和纳米酶在生物传感、生物催化、环境修复等多个领域的酶固定化研究现状，重点介绍了高选择性、高效生物催化方面存在的挑战和未来发展方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.