Optimal schemes for the use of anthelmintics at gastrointestinal strongylatosis of young cattle

I. Arkhipov, A. Varlamova, E. O. Kachanova
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Abstract

The purpose of the research is to study the rational terms for the use of anthelmintics in case of gastrointestinal strongylatoses of young cattle in Nonchernozem zone of the Russian Federation.Materials and methods. The timing of the onset of re-isolation of nematode eggs with feces of cattle after the use of some anthelmintics was determined on 50 black-motley calves weighing 117–130 kg, spontaneously infected with gastrointestinal strongylates. The optimal schemes for the use of anthelmintics in case of gastrointestinal strongylatosis of young cattle were studied on 109 calves of the first year of grazing in the pasture period of 2010. After numbering, the animals were weighed and divided into experimental and control groups. Each group was divided into two subgroups of 15–17 heads. Animals of all groups from May 3 to October 10, 2018 were grazed together in one herd on a pasture where cattle infected with strongylates had previously grazed. Levamisole from the group of imidothiazoles, Alben from the group of benzimidazoles and Aversect-2 from the group of macrocyclic lactones were tested. The drugs were used in therapeutic doses: levamisole at a dose of 7.5 mg/kg by AS intramuscularly, Alben at a dose of 7.5 mg/kg with concentrated feed, and Aversect-2 at a dose of 0.2 mg/kg subcutaneously once. Levamisole was administered to the animals of the first group on the 6th, 10th and 14th weeks of grazing, and to the animals of the second group - on the 6th and 10th weeks of grazing. Alben was used on young cattle of the third group on the 6th, 11th and 16th weeks, and on the animals of the fourth group - on the 6th and 11th weeks of grazing. Aversect-2 was administered to cattle of the fifth group at the 6th, 13th and 20th weeks of grazing, and to the animals of the sixth group – at the 6th and 13th weeks. Animals of the 7th group did not receive the drug and served as control. Fecal samples were taken from animals of all groups on a monthly basis and investigated by a quantitative method in order to detect eggs of gastrointestinal strongylate. The results obtained were statistically processed using the computer program Microsoft Excel.Results and discussion. Tests of drugs for gastrointestinal strongylatoses of young cattle showed different persistence of anthelmintic action. After deworming the animals, single eggs of strongylate in their faeces were again detected 4 weeks after the administration of Levamisole, 5 weeks after the administration of Alben, and 7 weeks after the administration of Aversect-2. The most rational scheme for deworming young cattle with gastrointestinal strongylatoses is the use of Aversect-2 on the 6th and 19th weeks of grazing.
对犊牛胃肠线虫病使用驱虫药的最佳方案
本研究的目的是研究在俄罗斯联邦非黑钙土地区幼牛胃肠道线虫病中使用驱虫剂的合理条件。材料和方法。在50头体重117-130公斤的黑斑蝥幼崽身上测定了在使用一些驱虫剂后,从牛粪便中重新分离线虫卵的时间,这些幼崽自发感染了胃肠道strongylates。在2010年放牧期间,对109头第一年放牧的小牛进行了研究,研究了在幼牛胃肠道strongylation情况下使用驱虫剂的最佳方案。编号后,对动物进行称重,并将其分为实验组和对照组。每组被分为两个小组,每组15-17人。2018年5月3日至10月10日,所有组别的动物被集中在一个牧场上放牧,此前曾在那里放牧过感染strongylates的牛。测试来自咪唑类的左旋咪唑、来自苯并咪唑类的Alben和来自大环内酯类的Aversect-2。药物按治疗剂量使用:AS肌肉注射左旋咪唑7.5 mg/kg,Alben浓缩饲料7.5 mg/kg,Aversect-2皮下注射0.2 mg/kg。第一组动物在放牧的第6、第10和第14周服用左旋咪唑,第二组动物在牧场的第6和第10周服用左旋唑。Alben在第6、11和16周用于第三组的幼牛,在第6和11周用于第四组的动物。第五组的牛在放牧的第6、13和20周服用Aversect-2,第六组的动物在第6和13周服用Aversect-2。第7组的动物没有接受该药物并作为对照。每月从所有组的动物身上采集粪便样本,并通过定量方法进行调查,以检测胃肠道strong酸盐的卵子。使用计算机程序Microsoft Excel对获得的结果进行统计处理。结果和讨论。对小牛胃肠道strongylatose的药物测试显示出不同的驱虫作用持久性。在给动物驱虫后,在给药左旋咪唑后4周、给药Alben后5周和给药Aversect-2后7周,再次在它们的粪便中检测到甲磺酸盐的单卵。对患有胃肠道strongylatose的幼牛进行驱虫的最合理方案是在放牧的第6周和第19周使用Aversect-2。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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