{"title":"Selectivity of Tryptophan and Phenylalanine Adsorption by Activated Coconut Carbon of Medical Assignment","authors":"I. A. Farbun, V. A. Trykhlib","doi":"10.1007/s11237-023-09766-5","DOIUrl":null,"url":null,"abstract":"<div><div><p>The adsorption capacity of carbon adsorbent KARBON™ for tryptophan and phenylalanine from the individual solutions, their mixtures, and in the presence of leucine, isoleucine, and valine has been studied. It is established that, at the adsorption from the mixture of these amino acids, the overall removal of tryptophan and phenylalanine is an order of magnitude exceeding the removal of aliphatic analogues. Maximum removals (>90%) of tryptophan and phenylalanine are achieved at concentrations of 2.0-2.8 mmol/L, as the concentrations increase to 20-24 mmol/L, the efficiency of the removal of these amino acids is decreased approximately twice. The obtained data show that the enterofraction of the adsorbent KARBON™ can be used as an alternative to amino acid therapy for various diseases.</p></div></div>","PeriodicalId":796,"journal":{"name":"Theoretical and Experimental Chemistry","volume":"59 1","pages":"59 - 65"},"PeriodicalIF":0.7000,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Theoretical and Experimental Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11237-023-09766-5","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 1
Abstract
The adsorption capacity of carbon adsorbent KARBON™ for tryptophan and phenylalanine from the individual solutions, their mixtures, and in the presence of leucine, isoleucine, and valine has been studied. It is established that, at the adsorption from the mixture of these amino acids, the overall removal of tryptophan and phenylalanine is an order of magnitude exceeding the removal of aliphatic analogues. Maximum removals (>90%) of tryptophan and phenylalanine are achieved at concentrations of 2.0-2.8 mmol/L, as the concentrations increase to 20-24 mmol/L, the efficiency of the removal of these amino acids is decreased approximately twice. The obtained data show that the enterofraction of the adsorbent KARBON™ can be used as an alternative to amino acid therapy for various diseases.
期刊介绍：
Theoretical and Experimental Chemistry is a journal for the rapid publication of research communications and reviews on modern problems of physical chemistry such as:
a) physicochemical bases, principles, and methods for creation of novel processes, compounds, and materials;
b) physicochemical principles of chemical process control, influence of external physical forces on chemical reactions;
c) physical nanochemistry, nanostructures and nanomaterials, functional nanomaterials, size-dependent properties of materials.
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