{"title":"Fine needle aspiration cytology of sacrococcygeal chordoma- utility in a case of clinical dilemma","authors":"Mamta Gupta, F. Lobo, D. Adiga","doi":"10.15406/icpjl.2017.04.00101","DOIUrl":null,"url":null,"abstract":"Chordoma was originally described by Virchow in 1857 and further characterized by Ribbert in 1894. It is a rare low to intermediate grade malignant notochordal tumor that recapitulates the notochord and has a tendency for recurrences and metastasis.1,2 They represent 1–4% of all malignant bone tumors. Most prevailing theory regarding the development of chordoma is that the notochord fails to degenerate and undergoes malignant transformation. Approximately 50% of chordomas are sacrococcygeal in origin and usually present as destructive bone lesions with a large soft tissue mass.3–5","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2017-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International clinical pathology journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/icpjl.2017.04.00101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Chordoma was originally described by Virchow in 1857 and further characterized by Ribbert in 1894. It is a rare low to intermediate grade malignant notochordal tumor that recapitulates the notochord and has a tendency for recurrences and metastasis.1,2 They represent 1–4% of all malignant bone tumors. Most prevailing theory regarding the development of chordoma is that the notochord fails to degenerate and undergoes malignant transformation. Approximately 50% of chordomas are sacrococcygeal in origin and usually present as destructive bone lesions with a large soft tissue mass.3–5