Antibacterial effects of the organic crude extracts of freshwater algae of Sulaymaniyah, Kurdistan Region, Iraq

N. Thomas, Rawa Raouf Ismail, A. Diyya, Dlzar D Ghafour, Lanya Karwan Jalal
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引用次数: 2

Abstract

In the recent past, the importance of freshwater algae has grown enormously due to their antibiotic activity against certain species of bacteria known for several disease states like endocarditis, external otitis, skin rash, etc. Also, there is a growing concern among the immunocompromised individuals that they may be susceptible to antibiotics and anti-fungal resistant infections resulting in increased fatality rates. Hence, in this investigation, extraction of potentially bioactive compounds from natural resources like freshwater algae was performed along with the evaluation of the antimicrobial activities of these extracts against some opportunistic bacteria like Staphylococcus aureus, Escherichia coli, Staphylococcus xylosus and Pseudomonas aeruginosa using well diffusion method. The data showed a statistically significant (P < 0.05) antibacterial activity of the organic extracts (0.1 g/ml) obtained from freshwater algae against multi-drug resistant S. aureus and S. xylosus strains as compared to the control. Our data reinforce the importance of bioactive compounds from fresh algae as potential antimicrobial agents, and they could act as an alternative to conventional antibiotics. Key words: Freshwater algae, Organic extracts, Antimicrobial activity, Opportunistic bacteria, Methicillin Resistant Streptococcus, Natural Antibiotics.
伊拉克库尔德斯坦苏莱曼尼亚淡水藻类有机粗提物的抗菌作用
在最近的一段时间里,淡水藻类的重要性已经大大提高,因为它们对某些细菌具有抗生素活性,这些细菌以心内膜炎、外耳道炎、皮疹等多种疾病而闻名。此外,免疫功能受损的个体越来越担心,他们可能对抗生素和抗真菌耐药性感染敏感,从而导致死亡率增加。因此,在本研究中,从淡水藻类等自然资源中提取了潜在的生物活性化合物,并使用井扩散法评估了这些提取物对金黄色葡萄球菌、大肠杆菌、木黄色葡萄球菌和绿脓杆菌等机会性细菌的抗微生物活性。数据显示,与对照相比,从淡水藻类中获得的有机提取物(0.1g/ml)对耐多药金黄色葡萄球菌和木糖菌株的抗菌活性具有统计学意义(P<0.05)。我们的数据强化了新鲜藻类中的生物活性化合物作为潜在抗菌剂的重要性,它们可以作为传统抗生素的替代品。关键词:淡水藻类,有机提取物,抗菌活性,机会细菌,耐甲氧西林链球菌,天然抗生素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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25
审稿时长
4.3 months
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