Research Progress on Mechanisms in Regulating Anxiety-Related Neural Circuits

Mengzhen Chen
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Abstract

Anxiety is a common disease in the modern society which significantly affects people’s daily lives and function, thus it has become an increasingly highlighted issue. Anxiety is regulated by neural circuits in the brain. Therefore, the basal mechanism of anxiety has been studied, especially research based on the related neural circuits. For a long time, due to the limitations of science and technology, there was no breakthrough in research regarding anxiety. However, in recent years, due to the progress of technology, the research on anxiety neural circuits has made great progress. For example, the interaction among various brain regions, such as the central nucleus of the amygdala (CeA), the ventral tegmental area (VTA), the ventral hippocampus (vHPC), and so on. This article focuses on three brain regions: including BLA, BNST, and VTA, and illustrate their different roles and mechanisms in regulating anxiety. On this basis, this intensive study of anxiety will further promote the progress of anxiety research and provide therapeutic targets for the related treatment.
焦虑相关神经回路调节机制的研究进展
焦虑是现代社会的一种常见疾病,严重影响着人们的日常生活和身体机能,已成为一个日益突出的问题。焦虑是由大脑中的神经回路控制的。因此,人们对焦虑的基本机制进行了研究,特别是基于相关神经回路的研究。长期以来,由于科学技术的限制,关于焦虑的研究一直没有突破。然而,近年来,由于技术的进步,对焦虑神经回路的研究取得了很大的进展。例如,大脑各区域之间的相互作用,如杏仁核中央核(CeA)、腹侧被盖区(VTA)、腹侧海马体(vHPC)等。本文重点介绍了脑区、中脑区和VTA在焦虑调节中的不同作用和机制。在此基础上,对焦虑的深入研究将进一步推动焦虑研究的进展,为相关治疗提供治疗靶点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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