Unilateral Usual Ductal Hyperplasia in A 22 Years Old Male Patient: A Case Report

Kelvin Setiawan, B. Rosadi, Terry Renata Lawanto, P. Rustamadji
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Abstract

Background: Benign breast disease have been broadly classified into non-proliferative lesions, proliferative lesions without atypia and hyperplasia with atypia. Proliferative disease, such as usual ductal hyperplasia, is associated with a 1.5 to 2 fold increased risk of developing invasive carcinoma. We reported a case of usual ductal hyperplasia in a young male. Case: A 22-year-old male complained of discomfort and enlargement of unilateral breast. Physical examination at that time revealed a palpable mass in the lateral upper quadrant of the patient’s left breast, three centimeters from nipple areola complex. The examination of axilla didn’t reveal any lymph node enlargement on both sides. His vital signs were normal without any abnormalities found on examination. Ultrasonography examination demonstrated fibroglandular tissue in the left breast with the volume of 11.13 cm3, consist of 4.8 cm length, 2.9 cm width and 0.8 cm depth. Excisional tumor biopsy was done on his left breast. Usual duct cell hyperplasia was present in microscopic examination with chronic inflammatory cells spreading around the fibrotic stromal cell. Physical examination, radiologic examination, and biopsy were all performed in this patient. Although the accuracy of the triple test is high, benign concordant results do not obviate further surveillance of a palpable mass. We advised our patient to routinely follow-up his condition every 6 months for 1 to 2 years, especially if there any changes found on his breasts. Conclusion: Any guidelines and further studies regarding patient’s follow-up examination after biopsy for male breasts tumor are needed in order of better understanding about this disease.
22岁男性单侧导管增生1例
背景:良性乳腺疾病广泛分为非增殖性病变、无异型性的增殖性病变和有异型性的增生性病变。增生性疾病,如常见的导管增生,与发展为浸润性癌的风险增加1.5至2倍有关。我们报告了一例年轻男性常见的导管增生。病例:一名22岁男性,主诉单侧乳房不适和增大。当时的体检显示,患者左乳房外侧上腹有一个可触摸的肿块,距离乳头乳晕复合体三厘米。腋窝检查未发现两侧淋巴结肿大。他的生命体征正常,检查没有发现任何异常。超声检查显示左乳纤维腺组织体积为11.13 cm3,长4.8 cm,宽2.9 cm,深0.8 cm。对他的左乳房进行了切除肿瘤活检。显微镜下可见常见的导管细胞增生,慢性炎症细胞在纤维化基质细胞周围扩散。对该患者进行了体格检查、放射学检查和活检。尽管三重检测的准确性很高,但良性一致的结果并不能排除对可触及肿块的进一步监测。我们建议患者每6个月定期随访一次,持续1至2年,尤其是在乳房有任何变化的情况下。结论:为了更好地了解男性乳腺肿瘤活检后的随访检查,需要任何指导方针和进一步的研究。
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审稿时长
24 weeks
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