A Narrative Review of Remimazolam in Procedural Sedation.

Q3 Medicine

Asian journal of anesthesiology Pub Date : 2023-06-14 DOI:10.6859/aja.202306/PP.0002

Geng-Ci Chen, Shih-Syuan Lin, Po-An Lin, W. Tseng, C‐H. Lu

引用次数: 0

Abstract

Remimazolam is a recently approved benzodiazepine for procedural sedation in Taiwan. It is a new type of short-acting γ-aminobutyric acid receptor agonist with the characteristics of non-organ-dependent metabolism, no injection pain, and inactive metabolites. Remimazolam has a mild cardiopulmonary suppressive effect, showing good effectiveness and safety in clinical applications, especially in the elderly, critically ill patients, or patients with hepatic and renal insufficiency. This review aims to provide an overview of the specific basic and clinical pharmacology of remimazolam and provide scientific support for the clinical application of this novel sedative drug in procedural sedation.

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雷米佐拉姆在《程序性镇静》中的叙事评论。

雷咪唑仑是台湾最近批准用于程序镇静的苯二氮卓类药物。是一种新型的短效γ-氨基丁酸受体激动剂，具有代谢不依赖器官、无注射痛、代谢产物无活性等特点。雷马唑仑具有轻微的心肺抑制作用，在临床应用中表现出良好的有效性和安全性，尤其适用于老年人、危重患者或肝肾功能不全患者。本文就雷马唑仑的具体基础和临床药理学进行综述，为这种新型镇静药物在手术镇静中的临床应用提供科学依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian journal of anesthesiology Medicine-Medicine (all)

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： Asian Journal of Anesthesiology (AJA), launched in 1962, is the official and peer-reviewed publication of the Taiwan Society of Anaesthesiologists. It is published quarterly (March/June/September/December) by Airiti and indexed in EMBASE, Medline, Scopus, ScienceDirect, SIIC Data Bases. AJA accepts submissions from around the world. AJA is the premier open access journal in the field of anaesthesia and its related disciplines of critical care and pain in Asia. The number of Chinese anaesthesiologists has reached more than 60,000 and is still growing. The journal aims to disseminate anaesthesiology research and services for the Chinese community and is now the main anaesthesiology journal for Chinese societies located in Taiwan, Mainland China, Hong Kong and Singapore. AJAcaters to clinicians of all relevant specialties and biomedical scientists working in the areas of anesthesia, critical care medicine and pain management, as well as other related fields (pharmacology, pathology molecular biology, etc). AJA''s editorial team is composed of local and regional experts in the field as well as many leading international experts. Article types accepted include review articles, research papers, short communication, correspondence and images.