Association between Flexible Nasal Endoscopy, Polysonography Findins and Obstructive Sleep Apnea Severety

Zappelini Cem, Jeremias La, Borba In, Machado Lz, Nicoladelli Sj, Marcelino Tf
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Abstract

Introduction: Obstructive Sleep Apnea (OSA) is a condition with recurrent collapses of the pharyngeal region that result in partial or total reduction in airflow. Its diagnosis and severity depends on the Apnea-Hypopnea Index (AHI), data from the polysomnography exam (PSG). Its pathophysiology includes anatomical disorders of the upper airways that can be assessed through Flexible Nasofibroscopy (FN). Objective: To identify the alterations present in the tests of FN and PSG in patients with OSA and correlate with the AHI. Methods: Cross-sectional study, with data collected from reports of the FN and PSG exams of 81 patients with OSA, seen at an otorhinolaryngology clinic in Tubarão - SC. It was verified the association between the outcome –AHI- and other exposure variables - sociodemographic and clinical. Results: Among the 81 patients, 75.31% were male, 41.98% had mild apnea, 30.86% moderate and 27.16% severe apnea. There was no correlation between FN findings and AHI (p> 0.05). There was a difference between the mean age, number of obstructive episodes per hour of sleep and minimum saturation between the groups with severe and mild apnea (p <0.05). Patients with severe apnea had a higher percentage of sleep phase one and a shorter REM sleep time compared to the mild apnea group (p <0.05). A positive correlation was obtained between: obstructive episodes with sleep stage 1 (p <0.01) and age (p <0.05); between minimum saturation and sleep stage 3 (p <0.05). There was an inverse correlation between obstructive episodes with minimal saturation (p <0.001), with sleep stage 3 (p <0.01) and with REM sleep (p <0.01); between age and minimum saturation (p <0.01). Conclusion: OSA directly interferes with sleep architecture. The present study did not find association between upper airway alterations and OSA severity.
柔性鼻内窥镜、多导成像结果与阻塞性睡眠呼吸暂停严重程度的关系
梗阻性睡眠呼吸暂停(OSA)是一种咽部反复塌陷导致部分或全部气流减少的病症。其诊断和严重程度取决于呼吸暂停低通气指数(AHI),多导睡眠图检查(PSG)的数据。其病理生理包括可通过柔性鼻纤维镜(FN)评估的上气道解剖紊乱。目的:探讨OSA患者FN和PSG检测的变化及其与AHI的相关性。方法:横断面研究,收集来自tubar o - SC的一家耳鼻喉科诊所的81例OSA患者的FN和PSG检查报告的数据,验证结果- ahi -与其他暴露变量-社会人口学和临床之间的关联。结果:81例患者中男性占75.31%,轻度呼吸暂停占41.98%,中度呼吸暂停占30.86%,重度呼吸暂停占27.16%。FN与AHI无相关性(p < 0.05)。重度和轻度呼吸暂停组的平均年龄、每小时睡眠阻塞发作次数和最低饱和度差异有统计学意义(p <0.05)。重度呼吸暂停患者的第一阶段睡眠比例高于轻度呼吸暂停组,REM睡眠时间较短(p <0.05)。睡眠阶段1阻塞性发作与年龄呈正相关(p <0.01);最低饱和度与睡眠阶段3之间的差异(p <0.05)。阻塞性发作与最低饱和度(p <0.001)、睡眠阶段3 (p <0.01)和快速眼动睡眠(p <0.01)呈负相关;年龄与最小饱和度之间有显著差异(p <0.01)。结论:OSA直接干扰睡眠结构。本研究未发现上呼吸道改变与OSA严重程度之间的关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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