Dye-Perfused Human Placenta for Simulation in a Microsurgery Laboratory for Plastic Surgeons.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Laura C Zambrano-Jerez, Karen D Díaz-Santamaría, María A Rodríguez-Santos, Diego F Alarcón-Ariza, Genny L Meléndez-Flórez, Mónica A Ramírez-Blanco
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Abstract

In recent decades, a number of simulation models for microsurgical training have been published. The human placenta has received extensive validation in microneurosurgery and is a useful instrument to facilitate learning in microvascular repair techniques as an alternative to using live animals. This study uses a straightforward, step-by-step procedure for instructing the creation of simulators with dynamic flow to characterize the placental vascular tree and assess its relevance for plastic surgery departments. Measurements of the placental vasculature and morphological characterization of 18 placentas were made. After the model was used in a basic microsurgery training laboratory session, a survey was given to nine plastic surgery residents, two microsurgeons, and one hand surgeon. In all divisions, venous diameters were larger than arterial diameters, with minimum diameters of 0.8 and 0.6 mm, respectively. The majority of the participants considered that the model faithfully reproduces a real microsurgical scenario; the consistency of the vessels and their dissection are similar in in vivo tissue. Furthermore, all the participants considered that this model could improve their surgical technique and would propose it for microsurgical training. As some of the model's disadvantages, an abundantly thick adventitia, a thin tunica media, and higher adherence to the underlying tissue were identified. The color-perfused placenta is an excellent tool for microsurgical training in plastic surgery. It can faithfully reproduce a microsurgical scenario, offering an abundance of vasculature with varying sizes similar to tissue in vivo, enhancing technical proficiency, and lowering patient error.

用于整形外科显微外科实验室模拟的染料灌注人胎盘
背景:胎盘作为模拟模型用于微血管修复技术的训练,作为活体动物使用的替代,主要在微神经外科中得到验证。本研究对胎盘血管树进行了表征,以确定其在显微外科训练中的适用性,并报告了住院医师和整形外科医生的评估结果。方法:测量胎盘血管,对18例胎盘进行形态学表征。该模型在显微外科基础培训实验室实施后,对9名整形外科住院医师、2名显微外科医生和1名手外科医生进行了调查。结果:各分区静脉直径均大于动脉直径,最小直径分别为0.8 mm和0.6 mm。大多数参与者认为,他们多少同意或绝对同意,该模型忠实地再现了真实的显微手术场景,血管的一致性及其解剖在体内组织中是相似的。此外,所有参与者都认为该模型可以提高他们的手术技术,减少错误,并将其作为显微外科培训的工具。作为该模型的一些缺点,我们确定了丰富的厚外膜,薄中膜和对下层组织的更高粘附性。结论:彩色灌注胎盘是整形外科显微外科训练的良好工具。它可以忠实地再现显微手术场景,提供丰富的血管,具有与体内组织相当的可变直径。这可以提高技术水平,减少患者失误
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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