A pilot study of exercise training for children and adolescents with inflammatory bowel disease: an evaluation of feasibility, safety, satisfaction, and efficacy

IF 1.4 4区医学 Q3 PEDIATRICS

Pediatric Exercise Science Pub Date : 2022-10-26 DOI:10.1101/2022.10.24.22279788

Mila Bjelica, Rachel G. Walker, J. Obeid, R. Issenman, B. Timmons

{"title":"A pilot study of exercise training for children and adolescents with inflammatory bowel disease: an evaluation of feasibility, safety, satisfaction, and efficacy","authors":"Mila Bjelica, Rachel G. Walker, J. Obeid, R. Issenman, B. Timmons","doi":"10.1101/2022.10.24.22279788","DOIUrl":null,"url":null,"abstract":"Abstract: Background: Children with inflammatory bowel disease (IBD) experience extra-intestinal side effects including altered body composition, impaired muscle strength and aerobic capacity. Exercise training may remedy these issues. Purpose: To assess the feasibility, safety, participant satisfaction and efficacy of a training program for youth with IBD. Methods: Children with IBD completed 16 weeks of training (2 supervised+1 home sessions per week). Feasibility was assessed by tracking recruitment, adherence, and compliance rates. Safety was assessed by tracking symptoms and adverse events. Post-training interviews gauged satisfaction. Circulating inflammatory markers, body composition, muscle strength, aerobic fitness, and habitual physical activity, were measured at baseline, mid-training (8 weeks), and post-training. Results: Eleven youth were recruited and 10 completed the study. Participants adhered to 28{+/-}1 of 32 prescribed supervised sessions and 8{+/-}4 of 16 prescribed home sessions. There were no adverse events, and overall feedback on training was positive. Post-training, we observed an increase in lean mass (+2.4{+/-}1.1 kg), bone density (+0.0124{+/-}0.015 g*cm-2), aerobic fitness (+2.8{+/-}5.7 mL*kgLM-1*min-1), and vigorous physical activity levels (+13.09{+/-} 8.95 min*hr-1) but no change in inflammation or muscle strength. Conclusion: Supervised exercise training is feasible, safe, and effective for youth with IBD and should be encouraged.","PeriodicalId":49712,"journal":{"name":"Pediatric Exercise Science","volume":"1 1","pages":"1-10"},"PeriodicalIF":1.4000,"publicationDate":"2022-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Exercise Science","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1101/2022.10.24.22279788","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}

引用次数: 0

Abstract

Abstract: Background: Children with inflammatory bowel disease (IBD) experience extra-intestinal side effects including altered body composition, impaired muscle strength and aerobic capacity. Exercise training may remedy these issues. Purpose: To assess the feasibility, safety, participant satisfaction and efficacy of a training program for youth with IBD. Methods: Children with IBD completed 16 weeks of training (2 supervised+1 home sessions per week). Feasibility was assessed by tracking recruitment, adherence, and compliance rates. Safety was assessed by tracking symptoms and adverse events. Post-training interviews gauged satisfaction. Circulating inflammatory markers, body composition, muscle strength, aerobic fitness, and habitual physical activity, were measured at baseline, mid-training (8 weeks), and post-training. Results: Eleven youth were recruited and 10 completed the study. Participants adhered to 28{+/-}1 of 32 prescribed supervised sessions and 8{+/-}4 of 16 prescribed home sessions. There were no adverse events, and overall feedback on training was positive. Post-training, we observed an increase in lean mass (+2.4{+/-}1.1 kg), bone density (+0.0124{+/-}0.015 g*cm-2), aerobic fitness (+2.8{+/-}5.7 mL*kgLM-1*min-1), and vigorous physical activity levels (+13.09{+/-} 8.95 min*hr-1) but no change in inflammation or muscle strength. Conclusion: Supervised exercise training is feasible, safe, and effective for youth with IBD and should be encouraged.

查看原文本刊更多论文

儿童和青少年炎症性肠病运动训练的初步研究：可行性、安全性、满意度和疗效评估

摘要：背景：患有炎症性肠病（IBD）的儿童会出现肠外副作用，包括身体成分改变、肌肉力量和有氧能力受损。运动训练可以解决这些问题。目的：评估青少年IBD培训计划的可行性、安全性、参与者满意度和有效性。方法：IBD儿童完成了16周的训练（每周2次监督+1次家庭训练）。通过跟踪招募、遵守和遵守率来评估可行性。通过追踪症状和不良事件来评估安全性。培训后的访谈衡量了满意度。在基线、训练中期（8周）和训练后测量循环炎症标志物、身体成分、肌肉力量、有氧健身和习惯性体育活动。结果：招募了11名青年，其中10人完成了研究。参与者参加了32次指定监督会议中的28次｛+/-｝1次和16次指定家庭会议中的8次｛+/-｝4次。没有发生不良事件，对培训的总体反馈是积极的。训练后，我们观察到体重增加（+2.4｛+/-｝1.1 kg）、骨密度增加（+0.0124｛+/-｝0.015 g*cm-2）、有氧健身增加（+2.8｛+/-｝5.7 mL*kgLM-1*min-1）和剧烈体力活动水平增加（+13.09｛+/-}8.95 min*hr-1），但炎症或肌肉力量没有变化。结论：有监督的运动训练对青少年IBD患者是可行、安全、有效的，应予以鼓励。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pediatric Exercise Science 医学-生理学

CiteScore

2.80

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Pediatric Exercise Science is a journal committed to enriching the scientific knowledge of exercise during childhood and adolescence. To this end it publishes information that contributes to an understanding of (a) the unique aspects of the physiologic, physical, biochemical, and psychologic responses of children to exercise, (b) the role of exercise in the treatment of pediatric chronic diseases, (c) the importance of physical activity in the prevention of illness and preservation of wellness, and (d) the means by which participation in sports may be made safer and more enjoyable for children and youth. Consideration will be given for publication of work by various methodologies consistent with the scientific approach. Besides original research, the journal includes review articles, abstracts from other journals, book reviews, and editorial comments. Pediatric Exercise Science encourages the expression of conflicting opinions regarding children and exercise by providing a forum for alternative viewpoints. At the same time it serves as a means of accumulating a base of research information that will allow application of experimental data to clinical practice. The scientific disciplines contributing to this body of knowledge are diverse. Therefore it is the purpose of this journal to provide a common focus for disseminating advances in the science of exercise during childhood. In doing so, the journal allows the opportunity for cross-fertilization of ideas between disciplines that will potentiate the growth of knowledge in this field. Pediatric Exercise Science seeks to stimulate new ideas regarding exercise in children and to increase the awareness of scientists, health care providers, and physical educators of the importance of exercise during childhood.