Diversity and features of proteins with structural repeats.

IF 4.9 Q1 BIOPHYSICS

Biophysical reviews Pub Date : 2023-09-07 eCollection Date: 2023-10-01 DOI:10.1007/s12551-023-01130-0

Evgeniya I Deryusheva, Andrey V Machulin, Oxana V Galzitskaya

引用次数: 0

Abstract

The review provides information on proteins with structural repeats, including their classification, characteristics, functions, and relevance in disease development. It explores methods for identifying structural repeats and specialized databases. The review also highlights the potential use of repeat proteins as drug design scaffolds and discusses their evolutionary mechanisms.

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具有结构重复的蛋白质的多样性及其特征

这篇综述提供了具有结构重复序列的蛋白质的信息，包括它们的分类、特征、功能和与疾病发展的相关性。它探讨了识别结构重复和专门数据库的方法。这篇综述还强调了重复蛋白作为药物设计支架的潜在用途，并讨论了它们的进化机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biophysical reviews Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

8.90

自引率

0.00%

发文量

期刊介绍： Biophysical Reviews aims to publish critical and timely reviews from key figures in the field of biophysics. The bulk of the reviews that are currently published are from invited authors, but the journal is also open for non-solicited reviews. Interested authors are encouraged to discuss the possibility of contributing a review with the Editor-in-Chief prior to submission. Through publishing reviews on biophysics, the editors of the journal hope to illustrate the great power and potential of physical techniques in the biological sciences, they aim to stimulate the discussion and promote further research and would like to educate and enthuse basic researcher scientists and students of biophysics. Biophysical Reviews covers the entire field of biophysics, generally defined as the science of describing and defining biological phenomenon using the concepts and the techniques of physics. This includes but is not limited by such areas as: - Bioinformatics - Biophysical methods and instrumentation - Medical biophysics - Biosystems - Cell biophysics and organization - Macromolecules: dynamics, structures and interactions - Single molecule biophysics - Membrane biophysics, channels and transportation