Using nanoparticles to prevent enamel wear

Q2 Materials Science
Yan Chen , Bradley T. Simon , Lynne A. Opperman , Peter Renner , Dilworth Parkinson , Alexander Sinyukov , Hong Liang
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引用次数: 2

Abstract

The objective of this research is to study the feasibility using nanomaterials to prevent and/or repair wear of teeth. Canine teeth have thin enamel prone to dental wear, causing pain, tooth loss, and infection. This research developed a new teeth repair agent based on the tribochemically active nanoparticles. The presence and properties of synthesized repair agents were evaluated after applying the repair agents by rubbing (simulated chewing) between extracted dog teeth. Polyether modified alpha‑zirconium phosphate (α-ZrP) nanoparticles form a strong and durable protective layer on a canine tooth's enamel surface through chewing. The effectiveness of this protective film generation was enhanced by adding hydroxyapatite (HAp) nanoparticles into the repair agent. This protective film is up to 2 μm thick and has a hardness comparable to the enamel substrate. These results show that by chewing with the repair agent, the teeth are protected. The tomography result shows this repair agent also has the potential to mend cracks on the enamel surface. This research reports a novel approach to protect the wear of teeth. Nanoparticles promoted the generation of a protective film in situ during the chewing process. This nanomaterial can be the base of novel dental protective devices such as chewing toys or gums that preventing or reversing tooth wear and reducing the stress and cost of dental restoration operations.

使用纳米颗粒防止牙釉质磨损
本研究的目的是研究使用纳米材料预防和/或修复牙齿磨损的可行性。犬牙的牙釉质很薄,容易磨损,导致疼痛、牙齿脱落和感染。本研究开发了一种基于摩擦化学活性纳米颗粒的新型牙齿修复剂。将合成的修复剂在犬拔牙间摩擦(模拟咀嚼),评价修复剂的存在和性能。聚醚修饰的α-磷酸锆(α-ZrP)纳米颗粒通过咀嚼在犬牙的牙釉质表面形成坚固耐用的保护层。在修复剂中加入羟基磷灰石(HAp)纳米颗粒可增强保护膜的生成效果。这种保护膜厚达2 μm,硬度与珐琅基材相当。这些结果表明,通过咀嚼修复剂,牙齿受到保护。断层扫描结果显示,该修复剂也具有修复牙釉质表面裂纹的潜力。本研究报告了一种保护牙齿磨损的新方法。纳米颗粒促进了咀嚼过程中保护膜的原位生成。这种纳米材料可以作为新型牙齿保护装置的基础,如咀嚼玩具或牙龈,防止或逆转牙齿磨损,减少牙齿修复手术的压力和成本。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biotribology
Biotribology Materials Science-Surfaces, Coatings and Films
CiteScore
4.20
自引率
0.00%
发文量
17
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