Analysis of Factors of Complications in Patients with Moyamoya Disease After Revascularization

Abstract

Objective: In this study, the driving factors of complications in patients with moyamoya disease after revascularization are analyzed and discussed. Methods: A total of 1500 cases with moyamoya disease after revascularization in Yunan Shuifu People’s Hosptial and Beijing University of Chinese Medicine Third Affiliated Hospital from November 2017 to November 2022 were selected retrospectively, and they were divided into an observation group (with postoperative complications) and a control group (with no complications), resulting in 313 cases and 1187 cases in each group, respectively. Univariate and multivariate analysis were performed to screen out independent risk factors for complications in patients with moyamoya disease after revascularization. Results: Univariate analysis showed that the proportion of patients with cerebral ischemia, history of hypertension, and modified Rankin scale (mRs) score of 3-5 in the observation group were significantly higher than those in the control group. Complications were used as the dependent variable, and the indicators with statistically significant differences based on the univariate analysis were included as independent variables in the logistic regression analysis. The results showed that the first symptoms before operation were cerebral ischemia, history of hypertension, and mRs score of 3 to 5 were risk factors for complications in patients with moyamoya disease after revascularization, and there were significant differences in the data (OR = 1.781, 1.811, 1.859, all P < 0.05). Conclusion: Cerebral ischemia is the first symptom before operation, and history of hypertension and mRs score of 3 to 5 are all risk factors for complications in patients with moyamoya disease after revascularization. Therefore, clinical prevention should be strengthened, and corresponding treatment measures should be given in time to reduce the risk of postoperative complications in patients with moyamoya disease.