Correlation Between the Level od Atherosclerosis and Pathological Features of Coronary Artery Disease: A Study of 100 Autopsy Cases

IF 0.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Clinical and Experimental Health Sciences Pub Date : 2022-12-25 DOI:10.33808/clinexphealthsci.1123538

Nurşen Turan Yurtsever, Süheyla Ekemen, Hüseyin Çetin Ketenci

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Abstract

Objective: Atherosclerosis is a generalized, chronic disease of large and medium-sized muscular elastic arteries. Relation between intensity of atherosclerosis and coronary artery disease, and risk factors of atherosclerosis could not been revealed completely by autopsy studies. We aimed to renew this shortage of knowledge with our autopsy study prospectively. Methods: One hundred cases were autopsied within 48 h after death. Atherosclerotic risk factor data were collected including age, gender, height, weight, smoking and any chronic coronary artery disease. Atherosclerosis severity was evaluated macroscopically by examining the inner surfaces of the vascular lumens and revealed with postmortem pathological findings of coronary artery disease. Results: The mean age was 42 ± 22 years. Seventy-four percent of cases were male, while 26% were female. Smoking duration ranged from 1 to 50 years with a mean duration of 17 ± 12 years. Existence of atherosclerosis in main vessels were also in correlation with age, duration of smoking and BMI (Body Mass Index) (p

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动脉粥样硬化程度与冠心病病理特征的相关性研究——附100例尸检报告

目的:动脉粥样硬化是一种大中型肌肉弹性动脉的全身性慢性疾病。动脉粥样硬化的强度与冠状动脉疾病的关系以及动脉粥样硬化的危险因素不能通过尸检研究完全揭示。我们的目标是通过前瞻性的尸检研究来弥补这一知识的不足。方法:100例患者死后48 h内尸检。收集动脉粥样硬化危险因素数据，包括年龄、性别、身高、体重、吸烟和任何慢性冠状动脉疾病。动脉粥样硬化的严重程度通过检查血管腔的内表面进行宏观评估，并与死后冠状动脉疾病的病理结果一起显示。结果:患者平均年龄42±22岁。74%的病例为男性，26%为女性。吸烟时间1 ~ 50年，平均17±12年。主要血管动脉粥样硬化的存在也与年龄、吸烟时间和身体质量指数(BMI)相关

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Clinical and Experimental Health Sciences MEDICINE, RESEARCH & EXPERIMENTAL-

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