In Vitro Antioxidant, Antifungal and Cytotoxic Activities of Selected Medicinal Plants of District Bannu and Lakki Marwat

Q2 Social Sciences

Studies on Ethno-Medicine Pub Date : 2017-07-03 DOI:10.1080/09735070.2017.1322368

Hassan Muhammad, S. M. Wazir, R. Khan

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引用次数: 4

Abstract

ABSTRACT In the present study, the researchers selected four plants from District Lakki Marwat and Bannu. The purpose of the study was evaluate the methanol extracts of these medicinal plants, namely, Tamarix aphylla, Euphorbia helioscopia, Coriandrum sativum and Peganum harmala for antimicrobial, antioxidant, and cytotoxic activities. Plants dried in shade, were ground and obtained their methanol extracts. The extracts were evaluated for biological assays using the standard protocol for in vitro study. For the study of cytotoxic properties of plants methanol extracts were used against brine shrimps and their antimicrobial activities were also measured. Antioxidant activities against different free radicals were also checked. Brine shrimps showed seventy percent mortality rate to Tamarix aphylla extract having concentration of 500 μg/ml. The scavenging activity for free radicals was also significant at 500μg/ml. The present study revealed that these activities may be owing to the presence of bioactive constituents, isolation and purification of which is necessary.

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Bannu和Lakki Marwat地区部分药用植物的体外抗氧化、抗真菌和细胞毒性活性

摘要在本研究中，研究人员从Lakki Marwat和Bannu地区选择了四种植物。本研究的目的是评估这些药用植物的甲醇提取物，即：七叶树、大戟、五味子和骆驼蓬的抗菌、抗氧化和细胞毒性活性。植物在阴凉处干燥，研磨并获得其甲醇提取物。使用体外研究的标准方案对提取物进行生物测定评估。为了研究植物的细胞毒性，采用甲醇提取物对卤虾进行了细胞毒性研究，并测定了其抗菌活性。还检测了对不同自由基的抗氧化活性。浓度为500μg／ml的鲎提取物对卤虾的致死率为70%。对自由基的清除活性在500μg/ml时也很显著。本研究表明，这些活性可能是由于存在生物活性成分，需要对其进行分离和纯化。

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来源期刊

Studies on Ethno-Medicine Social Sciences-Cultural Studies

CiteScore

0.50

自引率

0.00%

发文量

期刊介绍： Studies on Ethno-Medicine is a peer reviewed, internationally circulated journal. It publishes reports of original research, theoretical articles, timely reviews, brief communications, book reviews and other publications in the interdisciplinary field of ethno-medicine. The journal serves as a forum for physical, social and life scientists as well as for health professionals. The transdisciplinary areas covered by this journal include, but are not limited to, Physical Sciences, Anthropology, Sociology, Geography, Life Sciences, Environmental Sciences, Botany, Agriculture, Home Science, Zoology, Genetics, Biology, Medical Sciences, Public Health, Demography and Epidemiology. The journal publishes basic, applied and methodologically oriented research from all such areas. The journal is committed to prompt review, and priority publication is given to manuscripts with novel or timely findings, and to manuscript of unusual interest. Further, the manuscripts are categorised under three types, namely - Regular articles, Short Communications and Reviews. The researchers are invited to submit original papers in English (papers published elsewhere or under consideration elsewhere shall not be considered).