Effectiveness of infant feeding strategies to prevent mother-to-child HIV vertical transmission in Ekiti State

J. EsanAyodele., Omisakin Ct, Oyegue Kelvin, E. OyedeleTitilayo
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Abstract

Worldwide, the HIV epidemic has had a major impact on maternal, child health and survival. An estimated 12 million and 1.1 million were women and children respectively have been infected with HIV. During the last few years, about 30-50% of approximately 500,000 infants were infected with HIV worldwide annually through breastfeeding and 1600 new infections occur daily [1,2]. In 2012, 3.3 million children were living with HIV (Human Immunodeficiency virus) of who 260,000 were new infections. However, about 370, 000 children were infected newly with HIV through mother-to-child transmission [3]. Over 1,000 children were infected newly with HIV daily; out of these more than half die as a result of AIDS, because of inadequate access to HIV treatment. Globally, in the year 2011, about 34 million [31.4 million-35.9 million] people were living with HIV, including 3.4 million (3,000,000-3,800,000) children less than 15 years of age. In 2010, about 250,000 (220,000-290,000) children, less than 15 years of age, died from acquired immunodeficiency disease syndrome (AIDS) related causes [4]. Nigeria is one of the countries in Sub-Saharan Africa continues with the highest loads of pediatric AIDS [5]. In 2011, Nigeria had an estimated 440,000 children less than 15 years, living with HIV. Mother-tochild transmission (MTCT) accounts for 90% of HIV infections in children under the age of 15 years [4]. Prevention of motherto-child transmission (PMTCT) has become a key public health priority in Nigeria, a country faced with 56,681 annual HIVpositive births and more than 210,000 women living with HIV [6]. The national PMTCT programme in Nigeria commenced in 2002 with supports from the World Health Organization (WHO) and The United Nations Children’s Fund (UNICEF) [7]. There are about 1,216 PMTCT service points across the Nigeria presently. In 2009, 18.7% of pregnant women living with HIV received antiretroviral (ARV) agents to reduce the risk of mother-to-child transmission (MTCT), showing a significant increase in PMTCT coverage from 5.3% in 2007, although the coverage for ARV prophylaxis during the breastfeeding period has still remained low [8]. Providing ARV prophylaxis to pregnant women living with HIV has prevented Volume 5 Issue 2 2017
在埃基蒂州预防艾滋病毒母婴垂直传播的婴儿喂养战略的有效性
在世界范围内,艾滋病毒的流行对孕产妇、儿童的健康和生存产生了重大影响。估计分别有1200万和110万妇女和儿童感染了艾滋病毒。在过去几年中,全球每年约50万名婴儿中约有30-50%通过母乳喂养感染艾滋病毒,每天新增1600例感染[1,2]。2012年,330万儿童感染了艾滋病毒,其中26万是新感染者。然而,约有37万名儿童通过母婴传播新感染了艾滋病毒[3]。每天有1 000多名儿童新感染艾滋病毒;其中一半以上的人死于艾滋病,因为得不到足够的艾滋病毒治疗。2011年,全球约有3400万[3140万-3590万]人感染艾滋病毒,其中包括340万(3000000-3800万)15岁以下儿童。2010年,约有250000(22000-290000)名15岁以下的儿童死于获得性免疫缺陷综合征(艾滋病)相关原因[4]。尼日利亚是撒哈拉以南非洲地区儿童艾滋病发病率最高的国家之一[5]。2011年,尼日利亚估计有44万名15岁以下儿童感染艾滋病毒。母婴传播(MTCT)占15岁以下儿童艾滋病毒感染的90%[4]。预防母婴传播(PMTCT)已成为尼日利亚公共卫生的一个关键优先事项,该国每年有56681例艾滋病毒阳性新生儿,超过21万名妇女感染艾滋病毒[6]。尼日利亚的国家预防母婴传播方案始于2002年,得到了世界卫生组织(世界卫生组织)和联合国儿童基金会(儿童基金会)的支持[7]。目前,尼日利亚全国约有1216个PMTCT服务点。2009年,18.7%的艾滋病毒感染孕妇接受了抗逆转录病毒药物治疗,以降低母婴传播的风险,表明预防母婴传播的覆盖率从2007年的5.3%显著增加,尽管母乳喂养期间抗逆转录病毒预防的覆盖率仍然很低[8]。为感染艾滋病毒的孕妇提供抗逆转录病毒药物预防已阻止2017年第5卷第2期
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