The Use of the RELiZORB Immobilized Lipase Cartridge in Enterally-Fed Children With Cystic Fibrosis

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Topics in Clinical Nutrition Pub Date : 2022-10-01 DOI:10.1097/TIN.0000000000000300

Parasto Baghae Pour, S. Gregg, K. Coakley, L. F. Caffey, D. Cohen, O. Myers, D. Gonzales-Pacheco

引用次数: 0

Abstract

The objective of this retrospective study was to evaluate the impact of the RELiZORB immobilized lipase cartridge with overnight enteral nutrition (EN) on body mass index (BMI) or weight-for-length percentile, stool quality, and gastrointestinal (GI) symptoms in children with cystic fibrosis (CF) and pancreatic insufficiency. Frequency of diarrhea, steatorrhea, and malodorous stools significantly decreased at final visit compared with baseline (P = .008, P = .004, P = .031, respectively). Improved BMI or weight-for-length percentile was observed in 10 out of 16 participants; however, the change was not significant. RELiZORB use decreased frequency of most GI symptoms in pediatric patients with CF on EN.

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RELiZORB固定化脂肪酶试剂盒在肠内喂养囊性纤维化儿童中的应用

本回顾性研究的目的是评估RELiZORB固定化脂肪酶药筒与夜间肠内营养(EN)对囊性纤维化(CF)和胰腺功能不全儿童体重指数(BMI)或体重长度百分位数、粪便质量和胃肠道(GI)症状的影响。与基线相比，最后一次就诊时腹泻、脂肪漏和恶臭便的频率显著降低(P = 0.008, P = 0.004, P = 0.031)。16名参与者中有10人的BMI或体重长度百分位数有所改善;然而，这种变化并不显著。使用RELiZORB可降低EN上CF患儿大多数胃肠道症状的发生频率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Topics in Clinical Nutrition NUTRITION & DIETETICS-

CiteScore

0.90

自引率

20.00%

发文量

期刊介绍： Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.