The effect of supplemental oxygen on 6-minute walk test in chronic obstructive pulmonary disease patients

IF 1.1 Q4 IMMUNOLOGY
Farzin Ghiasi, Fatemeh Sajjadfar, S. Sadeghi
{"title":"The effect of supplemental oxygen on 6-minute walk test in chronic obstructive pulmonary disease patients","authors":"Farzin Ghiasi, Fatemeh Sajjadfar, S. Sadeghi","doi":"10.34172/ipp.2022.25262","DOIUrl":null,"url":null,"abstract":"Introduction: Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease that associated with abnormal airflow during respiration. It has been demonstrated that supplemental oxygen used in the time of exercise testing has a considerable positive effect in cases with COPD. Objectives: Present study was aimed to investigate the possible effects of supplemental oxygen on the outcomes of 6-minute walk test (6MWT). Patients and Methods: COPD cases were randomly divided into two groups (n= 50/each). Group1; patients who received nasal oxygen during the 6MWT, and group two were patients who did not receive supplemental oxygen during the test. Results: The Shapiro-Wilk test showed that the distribution of all parameters in two groups followed the normal distribution. The total distance walked was 431.54±40.76 m in the intervention group and 399.08±49.94 m in the control group, with a significant difference between the two groups (P= 0.001). After 6MWT, the mean of SpO2 in the intervention group was significantly higher than the control group (P= 0.002) and the degree of dyspnea was significantly lower than the control group (P= 0.031). Conclusion: Overall, supplemental oxygen has significant positive effects in COPD patients, but definitive commentary is needed for further studies. Trial registration: The trial protocol was approved by the Thai Clinical Trials Registry (identifier: TCTR20220122001; https://www.thaiclinicaltrials.org, ethical code; IR.MUI.MED.REC. 1396.308.3).","PeriodicalId":13454,"journal":{"name":"Immunopathologia Persa","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2022-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunopathologia Persa","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/ipp.2022.25262","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease that associated with abnormal airflow during respiration. It has been demonstrated that supplemental oxygen used in the time of exercise testing has a considerable positive effect in cases with COPD. Objectives: Present study was aimed to investigate the possible effects of supplemental oxygen on the outcomes of 6-minute walk test (6MWT). Patients and Methods: COPD cases were randomly divided into two groups (n= 50/each). Group1; patients who received nasal oxygen during the 6MWT, and group two were patients who did not receive supplemental oxygen during the test. Results: The Shapiro-Wilk test showed that the distribution of all parameters in two groups followed the normal distribution. The total distance walked was 431.54±40.76 m in the intervention group and 399.08±49.94 m in the control group, with a significant difference between the two groups (P= 0.001). After 6MWT, the mean of SpO2 in the intervention group was significantly higher than the control group (P= 0.002) and the degree of dyspnea was significantly lower than the control group (P= 0.031). Conclusion: Overall, supplemental oxygen has significant positive effects in COPD patients, but definitive commentary is needed for further studies. Trial registration: The trial protocol was approved by the Thai Clinical Trials Registry (identifier: TCTR20220122001; https://www.thaiclinicaltrials.org, ethical code; IR.MUI.MED.REC. 1396.308.3).
补充氧对慢性阻塞性肺疾病患者6分钟步行试验的影响
慢性阻塞性肺疾病(COPD)是一种与呼吸过程中气流异常相关的炎症性肺部疾病。已经证明,在运动试验时补充氧气对慢性阻塞性肺病患者有相当大的积极作用。目的:本研究旨在探讨补充氧对6分钟步行试验(6MWT)结果的可能影响。患者与方法:慢性阻塞性肺病患者随机分为两组,每组50例。Group1;6MWT期间接受鼻腔吸氧的患者和第二组是在测试期间未接受补充吸氧的患者。结果:经Shapiro-Wilk检验,两组各参数均服从正态分布。干预组总步行距离为431.54±40.76 m,对照组为399.08±49.94 m,两组比较差异有统计学意义(P= 0.001)。6MWT后,干预组SpO2均值显著高于对照组(P= 0.002),呼吸困难程度显著低于对照组(P= 0.031)。结论:总体而言,补充氧气对COPD患者有显著的积极作用,但需要进一步研究的明确评论。试验注册:试验方案已获泰国临床试验注册中心批准(标识符:TCTR20220122001;https://www.thaiclinicaltrials.org,道德准则;IR.MUI.MED.REC。1396.308.3)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.70
自引率
0.00%
发文量
65
审稿时长
3 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信