DYNAMICS OF AN SIRS EPIDEMIC MODEL WITH PERIODIC INFECTION RATE ON A SCALE-FREE NETWORK

IF 1.3 4区 数学 Q3 BIOLOGY
Hongquan Sun, Hong Li, Zhangsheng Zhu
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引用次数: 0

Abstract

Influenced by seasonal changes, the infection rate of many infectious diseases fluctuates in cycles. In this paper, we propose and investigate an SIRS model on a scale-free network. To model seasonality, we assume that the infection rate is periodic. The existence and positivity of solutions of the proposed model are proved and the basic reproduction number [Formula: see text] is defined. The global stability of steady states is determined by rigorous mathematical analysis. When [Formula: see text], the disease-free equilibrium [Formula: see text] is globally asymptotically stable. When [Formula: see text], the system has a unique positive periodic solution [Formula: see text], and [Formula: see text] is globally asymptotically stable. Numerical simulations are performed to support our theoretic results, and the effects of various parameters on the amplitude and mean of infected individuals are studied. The sensitivity of parameters of the basic reproduction number [Formula: see text] is solved by the Sobol global sensitivity analysis method, and the results show that the effects of the parameters [Formula: see text] and [Formula: see text] on [Formula: see text] are remarkable.
无标度网络上具有周期感染率的SIRS流行病模型的动力学
受季节变化的影响,许多传染病的感染率呈周期性波动。本文提出并研究了一个无标度网络上的SIRS模型。为了模拟季节性,我们假设感染率是周期性的。证明了模型解的存在性和正性,定义了基本再现数[公式:见文]。通过严格的数学分析,确定了稳态的全局稳定性。当[公式:见文]时,无病平衡[公式:见文]是全局渐近稳定的。当[公式:见文]时,系统具有唯一的正周期解[公式:见文],且[公式:见文]是全局渐近稳定的。数值模拟支持了理论结果,并研究了各参数对感染个体振幅和平均值的影响。采用Sobol全局灵敏度分析法求解基本再现数[公式:见文]参数的灵敏度,结果表明[公式:见文]和[公式:见文]参数对[公式:见文]的影响是显著的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.80
自引率
12.50%
发文量
31
审稿时长
1 months
期刊介绍: The Journal of Biological Systems is published quarterly. The goal of the Journal is to promote interdisciplinary approaches in Biology and in Medicine, and the study of biological situations with a variety of tools, including mathematical and general systems methods. The Journal solicits original research papers and survey articles in areas that include (but are not limited to): Complex systems studies; isomorphies; nonlinear dynamics; entropy; mathematical tools and systems theories with applications in Biology and Medicine. Interdisciplinary approaches in Biology and Medicine; transfer of methods from one discipline to another; integration of biological levels, from atomic to molecular, macromolecular, cellular, and organic levels; animal biology; plant biology. Environmental studies; relationships between individuals, populations, communities and ecosystems; bioeconomics, management of renewable resources; hierarchy theory; integration of spatial and time scales. Evolutionary biology; co-evolutions; genetics and evolution; branching processes and phyllotaxis. Medical systems; physiology; cardiac modeling; computer models in Medicine; cancer research; epidemiology. Numerical simulations and computations; numerical study and analysis of biological data. Epistemology; history of science. The journal will also publish book reviews.
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