Fuga paravalvular tras implante de ACURATE neo y neo2: estudio comparativo con cuantificaci�n de calcio

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

REC Interventional Cardiology Pub Date : 2023-05-12 DOI:10.24875/recic.m23000369

M. García-Guimarães, Dirk-Jan Van Ginkel, Benno J. Rensing, J. M. T. Berg, Uday Sonker, Thomas L. De Kroon, Robin H. Heijmen, Martin J. Swaans, L. Timmers

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Abstract

Introduction and objectives: Moderate or severe paravalvular leak (PVL) following transcatheter aortic valve implantation (TAVI) has been associated with worse outcomes. Aortic valve (AV) calcification is a strong predictor of PVL. ACURATE neo (Boston Scientific Corporation, United States) is a self-expanding transcatheter heart valve to treat degenerative aortic stenosis. We evaluated PVL after ACURATE neo and neo2 implantation, and the role of AV calcification. Methods: We analyzed patients referred for TAVI with ACURATE neo and neo2 from a large volume tertiary center. All cardiac computed tomography scans were analyzed using 3Mensio Structural Heart software (Pie Medical Imaging, The Netherlands). The volume of AV calcium was quantified using contrast-enhanced cardiac computed tomography series. The 30-day clinical and echocardiographic data were prospectively recorded. Results: We included 165 patients referred for TAVI with ACURATE (neo = 87; neo2 = 78). Median age was 82 years-old, 65% were women with a median EuroSCORE II of 4.7 [IQR, 2.4-6.1]. Patients in the neo group showed a larger amount of total AV calcium (320 mm 3 vs 200 mm 3 ; P = .0305). We found no significant inter-group differences regarding clinical outcomes both

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Acurate Neo和NeO2植入后瓣膜旁渗漏：与钙定量的比较研究

简介和目的:经导管主动脉瓣植入术(TAVI)后中度或重度瓣旁漏(PVL)与较差的预后相关。主动脉瓣钙化是PVL的重要预测指标。accurate neo(波士顿科学公司，美国)是一种自我扩张的经导管心脏瓣膜，用于治疗退行性主动脉瓣狭窄。我们评估了acate neo和neo2植入后的PVL，以及房室钙化的作用。方法:我们分析来自大容量三级中心的acatate neo和neo2转诊TAVI的患者。所有心脏计算机断层扫描使用3Mensio心脏结构软件(Pie Medical Imaging, The Netherlands)进行分析。采用增强心脏计算机断层扫描系列定量测定房室钙的体积。前瞻性记录30天临床及超声心动图资料。结果:我们纳入了165例使用accurate进行TAVI转诊的患者(neo = 87;Neo2 = 78)。年龄中位数为82岁，65%为女性，EuroSCORE II中位数为4.7 [IQR, 2.4-6.1]。neo组患者的总房室钙含量更高(320 mm 3 vs 200 mm 3;P = .0305)。我们发现两组间临床结果没有显著差异

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